12 items (Gallus gallus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	CYB5A	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. (138 aa)
	CYP2D6	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. (502 aa)
	CYP2C18	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	CYP3A5	Uncharacterized protein. (508 aa)
	CYP1A2	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
	CYB5B	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (144 aa)
	CYP3A4	Uncharacterized protein; Belongs to the cytochrome P450 family. (540 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (429 aa)
	COLEC11	Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis [...] (271 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	CYP2C23a	Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (491 aa)
	CYP1A1	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	CYP1A1	ENSGALP00000060844	ENSGALP00000039219	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.410
ACTB	MYC	ENSGALP00000060844	ENSGALP00000072090	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.856
CYB5A	CYP1A1	ENSGALP00000022250	ENSGALP00000039219	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.516
CYB5A	CYP1A2	ENSGALP00000022250	ENSGALP00000002016	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.618
CYB5A	CYP2C23a	ENSGALP00000022250	ENSGALP00000039271	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.426
CYB5A	CYP2D6	ENSGALP00000022250	ENSGALP00000019386	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family.	0.471
CYB5A	CYP3A4	ENSGALP00000022250	ENSGALP00000007048	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.408
CYB5A	CYP3A5	ENSGALP00000022250	ENSGALP00000007068	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	Uncharacterized protein.	0.487
CYB5B	CYP1A1	ENSGALP00000000933	ENSGALP00000039219	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.564
CYB5B	CYP1A2	ENSGALP00000000933	ENSGALP00000002016	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.597
CYB5B	CYP2C18	ENSGALP00000000933	ENSGALP00000008773	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.402
CYB5B	CYP2C23a	ENSGALP00000000933	ENSGALP00000039271	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.431
CYB5B	CYP2D6	ENSGALP00000000933	ENSGALP00000019386	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family.	0.524
CYB5B	CYP3A5	ENSGALP00000000933	ENSGALP00000007068	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Uncharacterized protein.	0.423
CYP1A1	ACTB	ENSGALP00000039219	ENSGALP00000060844	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.410
CYP1A1	CYB5A	ENSGALP00000039219	ENSGALP00000022250	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.	0.516
CYP1A1	CYB5B	ENSGALP00000039219	ENSGALP00000000933	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.564
CYP1A1	CYP1A2	ENSGALP00000039219	ENSGALP00000002016	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.958
CYP1A1	CYP2C18	ENSGALP00000039219	ENSGALP00000008773	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.924
CYP1A1	CYP2C23a	ENSGALP00000039219	ENSGALP00000039271	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.478