(11 nodes) (2012) Endocannabinoids measurement in human saliva as potential biomarker of obesity. network (Gallus gallus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	LOC769866	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (208 aa)
	HPRT1	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (330 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (107 aa)
	DAGLB	Lipase_3 domain-containing protein. (667 aa)
	PRTFDC1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (226 aa)
	NAPEPLD	Lactamase_B domain-containing protein. (463 aa)
	GHRL	Preproghrelin. (116 aa)
	FAAHL	Amidase domain-containing protein. (522 aa)
	PYY	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. (90 aa)
	FAAH	Amidase domain-containing protein. (576 aa)
	VDHAP	Vitamin D3 hydroxylase-associated protein; May have a vitamin D3 hydroxylase regulatory function. (613 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAGLB	FAAH	ENSGALP00000011520	ENSGALP00000060654	Lipase_3 domain-containing protein.	Amidase domain-containing protein.	0.876
DAGLB	FAAHL	ENSGALP00000011520	ENSGALP00000024250	Lipase_3 domain-containing protein.	Amidase domain-containing protein.	0.863
DAGLB	NAPEPLD	ENSGALP00000011520	ENSGALP00000013467	Lipase_3 domain-containing protein.	Lactamase_B domain-containing protein.	0.876
DAGLB	VDHAP	ENSGALP00000011520	ENSGALP00000072052	Lipase_3 domain-containing protein.	Vitamin D3 hydroxylase-associated protein; May have a vitamin D3 hydroxylase regulatory function.	0.877
FAAH	DAGLB	ENSGALP00000060654	ENSGALP00000011520	Amidase domain-containing protein.	Lipase_3 domain-containing protein.	0.876
FAAH	NAPEPLD	ENSGALP00000060654	ENSGALP00000013467	Amidase domain-containing protein.	Lactamase_B domain-containing protein.	0.973
FAAHL	DAGLB	ENSGALP00000024250	ENSGALP00000011520	Amidase domain-containing protein.	Lipase_3 domain-containing protein.	0.863
FAAHL	NAPEPLD	ENSGALP00000024250	ENSGALP00000013467	Amidase domain-containing protein.	Lactamase_B domain-containing protein.	0.967
GHRL	INS	ENSGALP00000013685	ENSGALP00000010567	Preproghrelin.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.990
GHRL	PYY	ENSGALP00000013685	ENSGALP00000059469	Preproghrelin.	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family.	0.978
HPRT1	INS	ENSGALP00000009829	ENSGALP00000010567	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.507
HPRT1	LOC769866	ENSGALP00000009829	ENSGALP00000008592	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.901
INS	GHRL	ENSGALP00000010567	ENSGALP00000013685	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Preproghrelin.	0.990
INS	HPRT1	ENSGALP00000010567	ENSGALP00000009829	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.507
INS	PYY	ENSGALP00000010567	ENSGALP00000059469	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family.	0.794
LOC769866	HPRT1	ENSGALP00000008592	ENSGALP00000009829	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.901
NAPEPLD	DAGLB	ENSGALP00000013467	ENSGALP00000011520	Lactamase_B domain-containing protein.	Lipase_3 domain-containing protein.	0.876
NAPEPLD	FAAH	ENSGALP00000013467	ENSGALP00000060654	Lactamase_B domain-containing protein.	Amidase domain-containing protein.	0.973
NAPEPLD	FAAHL	ENSGALP00000013467	ENSGALP00000024250	Lactamase_B domain-containing protein.	Amidase domain-containing protein.	0.967
NAPEPLD	VDHAP	ENSGALP00000013467	ENSGALP00000072052	Lactamase_B domain-containing protein.	Vitamin D3 hydroxylase-associated protein; May have a vitamin D3 hydroxylase regulatory function.	0.972