40 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VEGFC	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (586 aa)
	GNRH1	GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; Belongs to the GnRH family. (92 aa)
	UTS2	Preprourotensin II. (124 aa)
	EDN2	Endothelin-2. (179 aa)
	SS2	Somatostatin II. (101 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (107 aa)
	UTS2B	Uncharacterized protein. (126 aa)
	SST	Somatostatin-14; Somatostatin inhibits the release of somatotropin. (116 aa)
	PROK2	Prokineticin 2. (109 aa)
	FURIN	Trans Golgi network protease furin; Belongs to the peptidase S8 family. (789 aa)
	GHRL	Preproghrelin. (116 aa)
	TRH	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. (260 aa)
	CALCR	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
	NPY	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa)
	EDN1	Endothelin 1. (194 aa)
	IAPP	Amyloid protein. (135 aa)
	CORIN	Corin, serine peptidase. (1130 aa)
	PCSK1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (748 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1864 aa)
	PENK	Proenkephalin. (267 aa)
	NMU	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family. (181 aa)
	GAL	Galanin variant 1. (141 aa)
	SCG2	Secretogranin II. (629 aa)
	CCK	Cholecystokinin-70; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear (By similarity). It also decreases food intake and regulates gastrointestinal physiological processes. (130 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (1024 aa)
	TOR2A	Torsin family 2 member A. (251 aa)
	NMB	Uncharacterized protein. (159 aa)
	UCN3	Urocortin 3. (154 aa)
	CARTPT	CART prepropeptide. (111 aa)
	VEGFD	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (378 aa)
	ADM	Uncharacterized protein. (73 aa)
	PDGFA	Platelet-derived growth factor A chain long form; Belongs to the PDGF/VEGF growth factor family. (211 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4. (791 aa)
	PDGFD	Uncharacterized protein; Belongs to the PDGF/VEGF growth factor family. (389 aa)
	PCSK2	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (644 aa)
	APLN	Apelin. (78 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (643 aa)
	QRFP	Uncharacterized protein. (122 aa)
	NMS	Neuromedin S long isoform. (150 aa)
	PCSK7	P/Homo B domain-containing protein. (799 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADM	CALCR	ENSGALP00000058799	ENSGALP00000015462	Uncharacterized protein.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.984
ADM	EDN1	ENSGALP00000058799	ENSGALP00000020756	Uncharacterized protein.	Endothelin 1.	0.624
ADM	IAPP	ENSGALP00000058799	ENSGALP00000021476	Uncharacterized protein.	Amyloid protein.	0.959
ADM	VEGFC	ENSGALP00000058799	ENSGALP00000017608	Uncharacterized protein.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.445
APLN	GAL	ENSGALP00000069961	ENSGALP00000042337	Apelin.	Galanin variant 1.	0.633
APLN	GHRL	ENSGALP00000069961	ENSGALP00000013685	Apelin.	Preproghrelin.	0.458
APLN	INS	ENSGALP00000069961	ENSGALP00000010567	Apelin.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.481
APLN	NMS	ENSGALP00000069961	ENSGALP00000071415	Apelin.	Neuromedin S long isoform.	0.577
APLN	NMU	ENSGALP00000069961	ENSGALP00000031462	Apelin.	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family.	0.639
APLN	NPY	ENSGALP00000069961	ENSGALP00000017870	Apelin.	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.	0.763
APLN	PENK	ENSGALP00000069961	ENSGALP00000024825	Apelin.	Proenkephalin.	0.588
APLN	SS2	ENSGALP00000069961	ENSGALP00000004793	Apelin.	Somatostatin II.	0.541
APLN	SST	ENSGALP00000069961	ENSGALP00000011889	Apelin.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.541
CALCR	ADM	ENSGALP00000015462	ENSGALP00000058799	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.984
CALCR	IAPP	ENSGALP00000015462	ENSGALP00000021476	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Amyloid protein.	0.937
CALCR	QRFP	ENSGALP00000015462	ENSGALP00000071229	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.477
CARTPT	NMU	ENSGALP00000055746	ENSGALP00000031462	CART prepropeptide.	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family.	0.425
CARTPT	NPY	ENSGALP00000055746	ENSGALP00000017870	CART prepropeptide.	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.	0.694
CARTPT	PCSK1	ENSGALP00000055746	ENSGALP00000023612	CART prepropeptide.	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.	0.519
CARTPT	PENK	ENSGALP00000055746	ENSGALP00000024825	CART prepropeptide.	Proenkephalin.	0.445