(7 nodes) (2013) Trans-Lesion DNA Polymerases May Be Involved in Yeast Meiosis. network (Gallus gallus)

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Your Input:
	RAD52	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). (422 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	DAO	D-amino acid oxidase. (348 aa)
	ACO1	Cytoplasmic aconitate hydratase; Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding (By similarity). (916 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (382 aa)
	RAD50	Zinc-hook domain-containing protein. (1313 aa)
	RAD54L	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family. (804 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RAD50	RAD52	ENSGALP00000039135	ENSGALP00000063584	Zinc-hook domain-containing protein.	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	0.903
RAD50	RAD54L	ENSGALP00000039135	ENSGALP00000037559	Zinc-hook domain-containing protein.	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family.	0.518
RAD50	SPO11	ENSGALP00000039135	ENSGALP00000048999	Zinc-hook domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.612
RAD52	RAD50	ENSGALP00000063584	ENSGALP00000039135	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	Zinc-hook domain-containing protein.	0.903
RAD52	RAD54L	ENSGALP00000063584	ENSGALP00000037559	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family.	0.996
RAD52	SPO11	ENSGALP00000063584	ENSGALP00000048999	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	SPO11 initiator of meiotic double stranded breaks.	0.841
RAD54L	RAD50	ENSGALP00000037559	ENSGALP00000039135	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family.	Zinc-hook domain-containing protein.	0.518
RAD54L	RAD52	ENSGALP00000037559	ENSGALP00000063584	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family.	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	0.996
RAD54L	SPO11	ENSGALP00000037559	ENSGALP00000048999	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family.	SPO11 initiator of meiotic double stranded breaks.	0.851
SPO11	RAD50	ENSGALP00000048999	ENSGALP00000039135	SPO11 initiator of meiotic double stranded breaks.	Zinc-hook domain-containing protein.	0.612
SPO11	RAD52	ENSGALP00000048999	ENSGALP00000063584	SPO11 initiator of meiotic double stranded breaks.	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	0.841
SPO11	RAD54L	ENSGALP00000048999	ENSGALP00000037559	SPO11 initiator of meiotic double stranded breaks.	DNA repair and recombination protein RAD54-like; Involved in DNA repair and mitotic recombination; Belongs to the SNF2/RAD54 helicase family.	0.851