38 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NPFFR2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (422 aa)
	NPY	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa)
	TACR3	Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (439 aa)
	NPY1R	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (385 aa)
	NPY4R	Neuropeptide Y receptor 4; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	NPFFR1	Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family. (399 aa)
	TACR2	Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (338 aa)
	OXTR	Oxytocin-like receptor. (391 aa)
	OPN1MSW	Green-sensitive opsin; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (355 aa)
	GALR2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	NPY2R	Neuropeptide Y receptor type 2; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family. (385 aa)
	QRFP	Uncharacterized protein. (122 aa)
	TAC1	Tachykinin precursor 1. (114 aa)
	LOC420716	Prolactin-releasing peptide. (139 aa)
	PYY	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. (90 aa)
	QRFPR	Orexigenic neuropeptide QRFP receptor; Belongs to the G-protein coupled receptor 1 family. (430 aa)
	PRLH	Uncharacterized protein. (87 aa)
	TACR1	Substance P receptor; Belongs to the G-protein coupled receptor 1 family. (411 aa)
	SCT	Secretin. (157 aa)
	TRHR	Thyrotropin-releasing hormone receptor; Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (395 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa)
	PPY	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. (80 aa)
	GAL	Galanin variant 1. (141 aa)
	GALR1	Galanin receptor; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	NTS	Neurotensin. (164 aa)
	GHSR	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (561 aa)
	GRPR	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (387 aa)
	NPY5R	G_PROTEIN_RECEP_F1_2 domain-containing protein. (443 aa)
	NPVF	Gonadotropin-inhibitory hormone. (173 aa)
	CGNRH-R	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	GNRHR	Type 1/III gonadotropin-releasing hormone receptor hexahelical variant. (354 aa)
	RHO	Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (351 aa)
	PRLHR	G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa)
	NMU	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family. (181 aa)
	MLNR	Motilin receptor MTL-R/GPR38; Belongs to the G-protein coupled receptor 1 family. (349 aa)
	NMBR	Neuromedin-B receptor; Belongs to the G-protein coupled receptor 1 family. (388 aa)
	SPX	Spexin hormone. (116 aa)
	GALR3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CGNRH-R	GNRHR	ENSGALP00000033143	ENSGALP00000032941	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Type 1/III gonadotropin-releasing hormone receptor hexahelical variant.	0.905
CGNRH-R	NPVF	ENSGALP00000033143	ENSGALP00000037048	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Gonadotropin-inhibitory hormone.	0.844
CGNRH-R	NPY	ENSGALP00000033143	ENSGALP00000017870	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.	0.432
CGNRH-R	SPX	ENSGALP00000033143	ENSGALP00000021648	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Spexin hormone.	0.409
GAL	GALR1	ENSGALP00000042337	ENSGALP00000041025	Galanin variant 1.	Galanin receptor; Belongs to the G-protein coupled receptor 1 family.	0.999
GAL	GALR2	ENSGALP00000042337	ENSGALP00000002895	Galanin variant 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.972
GAL	GALR3	ENSGALP00000042337	ENSGALP00000020087	Galanin variant 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.982
GAL	GRPR	ENSGALP00000042337	ENSGALP00000040632	Galanin variant 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.407
GAL	NMBR	ENSGALP00000042337	ENSGALP00000022379	Galanin variant 1.	Neuromedin-B receptor; Belongs to the G-protein coupled receptor 1 family.	0.457
GAL	NMU	ENSGALP00000042337	ENSGALP00000031462	Galanin variant 1.	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family.	0.733
GAL	NPY	ENSGALP00000042337	ENSGALP00000017870	Galanin variant 1.	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.	0.932
GAL	NPY2R	ENSGALP00000042337	ENSGALP00000072258	Galanin variant 1.	Neuropeptide Y receptor type 2; Receptor for neuropeptide Y and peptide YY; Belongs to the G-protein coupled receptor 1 family.	0.478
GAL	NPY5R	ENSGALP00000042337	ENSGALP00000037996	Galanin variant 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.415
GAL	NTS	ENSGALP00000042337	ENSGALP00000040948	Galanin variant 1.	Neurotensin.	0.812
GAL	PRLHR	ENSGALP00000042337	ENSGALP00000032414	Galanin variant 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.413
GAL	PYY	ENSGALP00000042337	ENSGALP00000059469	Galanin variant 1.	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family.	0.538
GAL	QRFP	ENSGALP00000042337	ENSGALP00000071229	Galanin variant 1.	Uncharacterized protein.	0.454
GAL	SCT	ENSGALP00000042337	ENSGALP00000047833	Galanin variant 1.	Secretin.	0.413
GAL	SPX	ENSGALP00000042337	ENSGALP00000021648	Galanin variant 1.	Spexin hormone.	0.601
GAL	TAC1	ENSGALP00000042337	ENSGALP00000063503	Galanin variant 1.	Tachykinin precursor 1.	0.693