(6 nodes) (2014) A DNA repair variant in POLQ (c.-1060A > G) is associated to hereditary breast cancer patients: a case-control study. network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	YY2	Uncharacterized protein. (420 aa)
	BRCA1	Uncharacterized protein. (1749 aa)
	BRCA2	Tower domain-containing protein. (3397 aa)
	ATM	Non-specific serine/threonine protein kinase. (3050 aa)
	SCRT2	Zinc finger transcription factor. (276 aa)
	CHEK2	Uncharacterized protein. (524 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	BRCA1	ENSGALP00000027660	ENSGALP00000004383	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.999
ATM	BRCA2	ENSGALP00000027660	ENSGALP00000027524	Non-specific serine/threonine protein kinase.	Tower domain-containing protein.	0.973
ATM	CHEK2	ENSGALP00000027660	ENSGALP00000049784	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.995
BRCA1	ATM	ENSGALP00000004383	ENSGALP00000027660	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.999
BRCA1	BRCA2	ENSGALP00000004383	ENSGALP00000027524	Uncharacterized protein.	Tower domain-containing protein.	0.999
BRCA1	CHEK2	ENSGALP00000004383	ENSGALP00000049784	Uncharacterized protein.	Uncharacterized protein.	0.982
BRCA2	ATM	ENSGALP00000027524	ENSGALP00000027660	Tower domain-containing protein.	Non-specific serine/threonine protein kinase.	0.973
BRCA2	BRCA1	ENSGALP00000027524	ENSGALP00000004383	Tower domain-containing protein.	Uncharacterized protein.	0.999
BRCA2	CHEK2	ENSGALP00000027524	ENSGALP00000049784	Tower domain-containing protein.	Uncharacterized protein.	0.906
CHEK2	ATM	ENSGALP00000049784	ENSGALP00000027660	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.995
CHEK2	BRCA1	ENSGALP00000049784	ENSGALP00000004383	Uncharacterized protein.	Uncharacterized protein.	0.982
CHEK2	BRCA2	ENSGALP00000049784	ENSGALP00000027524	Uncharacterized protein.	Tower domain-containing protein.	0.906