STRINGSTRING
LOC395381 LOC395381 PIGR PIGR VTG2 VTG2 LOC425137 LOC425137 SPINK5 SPINK5 HSD17B2 HSD17B2 CPB1 CPB1 CPA1 CPA1 FGG FGG SERPINH1 SERPINH1 GC GC LOC418170 LOC418170 AKR1B10 AKR1B10 IFI6 IFI6 TTR TTR ALDH1A1 ALDH1A1 LYG2 LYG2 SLC15A1 SLC15A1 FGL1L FGL1L OASL OASL RSFR RSFR HBE1 HBE1 ALDOB ALDOB FGB FGB B2M B2M AKR1E2 AKR1E2 ALB ALB IFI30 IFI30 GNLY GNLY ATP5O ATP5O TPM2 TPM2 HBAD HBAD PRSS2 PRSS2 LOC769668 LOC769668 CALB1 CALB1 AMY2A AMY2A MT-CO2 MT-CO2 PRSS3 PRSS3 DMBT1L-2 DMBT1L-2 TBP TBP CTSG CTSG DMBT1L DMBT1L GAPDH GAPDH CUZD1 CUZD1 CELA2A CELA2A MUC13 MUC13 ANGPTL1 ANGPTL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC395381Mucin-5B; Ovomucin, the glycoprotein responsible for the gel properties of egg white, is composed for 2 subunits, alpha-ovomucin/MUC5B and beta-ovomucin/MUC6. (2108 aa)
PIGRIg-like domain-containing protein. (648 aa)
VTG2Lipovitellin-1; Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms. (1854 aa)
LOC425137Aldo_ket_red domain-containing protein. (316 aa)
SPINK5Ovoinhibitor; Seems to have at least five active inhibitory domains; two for trypsin, two for chymotrypsin and one for elastase. (517 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (384 aa)
CPB1Uncharacterized protein. (417 aa)
CPA1Uncharacterized protein. (435 aa)
FGGFibrinogen C-terminal domain-containing protein. (438 aa)
SERPINH1Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. (405 aa)
GCUncharacterized protein. (484 aa)
LOC418170Aldo_ket_red domain-containing protein. (314 aa)
AKR1B10Aldo-keto reductase. (317 aa)
IFI6Putative ISG12(2) protein. (107 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (168 aa)
ALDH1A1Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity). (509 aa)
LYG2Lysozyme g; Belongs to the glycosyl hydrolase 23 family. (211 aa)
SLC15A1Peptide transporter PEPT1. (714 aa)
FGL1LFibrinogen C-terminal domain-containing protein. (258 aa)
OASLUncharacterized protein. (484 aa)
RSFRRibonuclease homolog. (139 aa)
HBE1Beta-H globin; Belongs to the globin family. (147 aa)
ALDOBFructose-bisphosphate aldolase B. (364 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. (488 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
AKR1E2Aldo_ket_red domain-containing protein. (316 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family. (565 aa)
IFI30IFI30 lysosomal thiol reductase. (411 aa)
GNLYNK-lysin. (140 aa)
ATP5OUncharacterized protein. (249 aa)
TPM2Tropomyosin beta chain; Belongs to the tropomyosin family. (335 aa)
HBADHemoglobin subunit alpha-D; Involved in oxygen transport from the lung to the various peripheral tissues. (141 aa)
PRSS2Trypsin II-P29; Belongs to the peptidase S1 family. (248 aa)
LOC769668Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
CALB1Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. (262 aa)
AMY2AAlpha-amylase. (512 aa)
MT-CO2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
PRSS3Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (259 aa)
DMBT1L-2Uncharacterized protein. (987 aa)
TBPTATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (302 aa)
CTSGPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
DMBT1LUncharacterized protein. (926 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
CUZD1ZP domain-containing protein. (379 aa)
CELA2APeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (323 aa)
MUC13Uncharacterized protein. (627 aa)
ANGPTL1Fibrinogen C-terminal domain-containing protein. (530 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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