(9 nodes) (2017) SNM1BApollo in the DNA damage response and telomere maintenance. network (Gallus gallus)

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Your Input:
	XRCC6	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic s [...] (647 aa)
	RAD50	Zinc-hook domain-containing protein. (1313 aa)
	ATM	Non-specific serine/threonine protein kinase. (3050 aa)
	EME1	Essential meiotic structure-specific endonuclease 1. (568 aa)
	POLN	POLAc domain-containing protein. (307 aa)
	FANCI	Uncharacterized protein. (1339 aa)
	FANCD2	Uncharacterized protein. (1510 aa)
	PHTF1	Putative homeodomain transcription factor 1. (752 aa)
	PRKDC	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act a [...] (4132 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	EME1	ENSGALP00000027660	ENSGALP00000012430	Non-specific serine/threonine protein kinase.	Essential meiotic structure-specific endonuclease 1.	0.513
ATM	FANCD2	ENSGALP00000027660	ENSGALP00000005896	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.929
ATM	FANCI	ENSGALP00000027660	ENSGALP00000010756	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.840
ATM	POLN	ENSGALP00000027660	ENSGALP00000025261	Non-specific serine/threonine protein kinase.	POLAc domain-containing protein.	0.511
ATM	PRKDC	ENSGALP00000027660	ENSGALP00000059070	Non-specific serine/threonine protein kinase.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act a [...]	0.774
ATM	RAD50	ENSGALP00000027660	ENSGALP00000039135	Non-specific serine/threonine protein kinase.	Zinc-hook domain-containing protein.	0.994
ATM	XRCC6	ENSGALP00000027660	ENSGALP00000053314	Non-specific serine/threonine protein kinase.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic s [...]	0.987
EME1	ATM	ENSGALP00000012430	ENSGALP00000027660	Essential meiotic structure-specific endonuclease 1.	Non-specific serine/threonine protein kinase.	0.513
EME1	FANCD2	ENSGALP00000012430	ENSGALP00000005896	Essential meiotic structure-specific endonuclease 1.	Uncharacterized protein.	0.827
EME1	FANCI	ENSGALP00000012430	ENSGALP00000010756	Essential meiotic structure-specific endonuclease 1.	Uncharacterized protein.	0.779
EME1	PRKDC	ENSGALP00000012430	ENSGALP00000059070	Essential meiotic structure-specific endonuclease 1.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act a [...]	0.481
FANCD2	ATM	ENSGALP00000005896	ENSGALP00000027660	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.929
FANCD2	EME1	ENSGALP00000005896	ENSGALP00000012430	Uncharacterized protein.	Essential meiotic structure-specific endonuclease 1.	0.827
FANCD2	FANCI	ENSGALP00000005896	ENSGALP00000010756	Uncharacterized protein.	Uncharacterized protein.	0.999
FANCD2	POLN	ENSGALP00000005896	ENSGALP00000025261	Uncharacterized protein.	POLAc domain-containing protein.	0.875
FANCD2	PRKDC	ENSGALP00000005896	ENSGALP00000059070	Uncharacterized protein.	DNA-dependent protein kinase catalytic subunit; Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act a [...]	0.779
FANCD2	XRCC6	ENSGALP00000005896	ENSGALP00000053314	Uncharacterized protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic s [...]	0.837
FANCI	ATM	ENSGALP00000010756	ENSGALP00000027660	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.840
FANCI	EME1	ENSGALP00000010756	ENSGALP00000012430	Uncharacterized protein.	Essential meiotic structure-specific endonuclease 1.	0.779
FANCI	FANCD2	ENSGALP00000010756	ENSGALP00000005896	Uncharacterized protein.	Uncharacterized protein.	0.999