STRINGSTRING
ATG16L1 ATG16L1 MAP1A MAP1A CD8A-3 CD8A-3 LOC424917 LOC424917 CD4 CD4 MUC4 MUC4 CD8A-2 CD8A-2 TIMD4 TIMD4 HSPA8 HSPA8 ATG7 ATG7 ATG5 ATG5 AAK1 AAK1 ATG10 ATG10 OVAL OVAL ATG3 ATG3 MTOR MTOR ATG12 ATG12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG16L1Autophagy related 16 like 1. (623 aa)
MAP1AMicrotubule associated protein 1A. (3023 aa)
CD8A-3Ig-like domain-containing protein. (318 aa)
LOC424917Uncharacterized protein. (2132 aa)
CD4Uncharacterized protein. (487 aa)
MUC4Uncharacterized protein. (3449 aa)
CD8A-2Ig-like domain-containing protein. (235 aa)
TIMD4Uncharacterized protein. (611 aa)
HSPA8Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] (638 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (709 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa)
AAK1AP2 associated kinase 1. (877 aa)
ATG10Autophagy related 10. (227 aa)
OVALOvalbumin; Non-inhibitory serpin. Storage protein of egg white. (386 aa)
ATG3Autophagy-related protein 3. (313 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2521 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (146 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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