STRINGSTRING
TF TF LOC416959 LOC416959 TLR3 TLR3 AvBD10 AvBD10 AvBD3 AvBD3 DEFB4A DEFB4A AvBD7 AvBD7 AvBD11 AvBD11 MELTF MELTF AvBD4 AvBD4 AvBD1 AvBD1 AvBD8 AvBD8 AvBD9 AvBD9 IFNW1 IFNW1 AvBD5 AvBD5 DUT DUT AvBD14 AvBD14 TLR15 TLR15 TLR7 TLR7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFOvotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. There are two forms of hen transferrin, ovotransferrin, found in the ovoducts and, serum transferrin, secreted by the liver. Serum transferrin may also have a role in stimulating cell proliferation and is regulated by iron levels. Ovotransferrin has a bacteriostatic function and, is not controlled by iron levels. (756 aa)
LOC416959Ovotransferrin; Belongs to the transferrin family. (738 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
AvBD10Gallinacin-10; Has bactericidal activity. (68 aa)
AvBD3Gallinacin-3; Has bactericidal activity. (80 aa)
DEFB4AGallinacin-2; Potent antibacterial activity against the Gram-negative bacterium E.coli ML-35, and against the Gram-positive bacterium L.monocytogenes EGD. Lacks antifungal activity against C.albicans. (64 aa)
AvBD7Gallinacin-7; Has bactericidal activity. (67 aa)
AvBD11Gallinacin-11; Has bactericidal activity. (104 aa)
MELTFOvotransferrin; Belongs to the transferrin family. (738 aa)
AvBD4Gallinacin-4; Has bactericidal activity. Potent activity against S.typhimurium and S.entiriditis. (63 aa)
AvBD1Gallinacin-1; Has bactericidal activity. Potent activity against E.coli ML- 35, L.monocytogenes EGD and C.albicans. (65 aa)
AvBD8Gallinacin-8; Has bactericidal activity. (66 aa)
AvBD9Gallinacin-9; Has bactericidal activity. Potent activity against C.jejuni, C.perfringens, S.aureus, C.albicans and S.cerevisiae. Less potent against S.typhimurium and E.coli. (67 aa)
IFNW1Interferon type B; Has antiviral activities; Belongs to the alpha/beta interferon family. (203 aa)
AvBD5Gallinacin-5; Has bactericidal activity. (66 aa)
DUTdUTPase domain-containing protein. (187 aa)
AvBD14Gallinacin-14; Has bactericidal activity; Belongs to the beta-defensin family. (64 aa)
TLR15TIR domain-containing protein. (924 aa)
TLR7Toll-like receptor 7; Belongs to the Toll-like receptor family. (1059 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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