STRINGSTRING
STAT3 STAT3 RPLP0 RPLP0 TRH TRH HCRT HCRT MC4R MC4R SPX SPX MCHR1 MCHR1 NMU NMU LEPR LEPR GNRHR GNRHR MC3R MC3R TMEM50A TMEM50A ADCYAP1 ADCYAP1 POMC POMC CNR1 CNR1 APLN APLN AGRP AGRP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT3Signal transducer and activator of transcription 3; Transcription factor that binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute-phase protein genes. (771 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10; Belongs to the universal ribosomal protein uL10 family. (350 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. (260 aa)
HCRTUncharacterized protein. (148 aa)
MC4RG_PROTEIN_RECEP_F1_2 domain-containing protein. (331 aa)
SPXSpexin hormone. (116 aa)
MCHR1Melanin concentrating hormone receptor 1. (367 aa)
NMUNeuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family. (181 aa)
LEPRUncharacterized protein. (1148 aa)
GNRHRType 1/III gonadotropin-releasing hormone receptor hexahelical variant. (354 aa)
MC3RMelanocortin 3 receptor. (325 aa)
TMEM50ATransmembrane protein 50A. (157 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family. (172 aa)
POMCUncharacterized protein. (251 aa)
CNR1Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family. (495 aa)
APLNApelin. (78 aa)
AGRPAgouti-related protein. (233 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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