node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYB5A | CYP1A1 | ENSGALP00000022250 | ENSGALP00000039219 | Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.516 |
CYB5A | CYP1A2 | ENSGALP00000022250 | ENSGALP00000002016 | Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. | Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.618 |
CYB5A | CYP2D6 | ENSGALP00000022250 | ENSGALP00000019386 | Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. | Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. | 0.471 |
CYB5A | CYP3A4 | ENSGALP00000022250 | ENSGALP00000007048 | Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.408 |
CYB5A | CYP3A5 | ENSGALP00000022250 | ENSGALP00000007068 | Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. | Uncharacterized protein. | 0.487 |
CYB5B | CYP1A1 | ENSGALP00000000933 | ENSGALP00000039219 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.564 |
CYB5B | CYP1A2 | ENSGALP00000000933 | ENSGALP00000002016 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.597 |
CYB5B | CYP1B1 | ENSGALP00000000933 | ENSGALP00000048510 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.405 |
CYB5B | CYP2C18 | ENSGALP00000000933 | ENSGALP00000008773 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.402 |
CYB5B | CYP2D6 | ENSGALP00000000933 | ENSGALP00000019386 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. | 0.524 |
CYB5B | CYP3A5 | ENSGALP00000000933 | ENSGALP00000007068 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | Uncharacterized protein. | 0.423 |
CYP1A1 | CYB5A | ENSGALP00000039219 | ENSGALP00000022250 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome b5; Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. | 0.516 |
CYP1A1 | CYB5B | ENSGALP00000039219 | ENSGALP00000000933 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.564 |
CYP1A1 | CYP1A2 | ENSGALP00000039219 | ENSGALP00000002016 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | 0.958 |
CYP1A1 | CYP1B1 | ENSGALP00000039219 | ENSGALP00000048510 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. | 0.932 |
CYP1A1 | CYP2C18 | ENSGALP00000039219 | ENSGALP00000008773 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.924 |
CYP1A1 | CYP2D6 | ENSGALP00000039219 | ENSGALP00000019386 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. | 0.560 |
CYP1A1 | CYP3A4 | ENSGALP00000039219 | ENSGALP00000007048 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.960 |
CYP1A1 | CYP3A5 | ENSGALP00000039219 | ENSGALP00000007068 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Uncharacterized protein. | 0.970 |
CYP1A1 | HMOX1 | ENSGALP00000039219 | ENSGALP00000036970 | Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. | Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. | 0.482 |