10 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYP1A2	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
	CYP3A5	Uncharacterized protein. (508 aa)
	GPX7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
	CYP1A1	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
	GPX8	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
	GPX1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (182 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
	CYP1C1	Uncharacterized protein; Belongs to the cytochrome P450 family. (516 aa)
	GPX4	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP1A1	CYP1A2	ENSGALP00000039219	ENSGALP00000002016	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.958
CYP1A1	CYP1B1	ENSGALP00000039219	ENSGALP00000048510	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.932
CYP1A1	CYP3A5	ENSGALP00000039219	ENSGALP00000007068	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein.	0.970
CYP1A2	CYP1A1	ENSGALP00000002016	ENSGALP00000039219	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.958
CYP1A2	CYP1B1	ENSGALP00000002016	ENSGALP00000048510	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.932
CYP1A2	CYP3A5	ENSGALP00000002016	ENSGALP00000007068	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein.	0.973
CYP1B1	CYP1A1	ENSGALP00000048510	ENSGALP00000039219	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.932
CYP1B1	CYP1A2	ENSGALP00000048510	ENSGALP00000002016	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.932
CYP1B1	CYP3A5	ENSGALP00000048510	ENSGALP00000007068	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.500
CYP1C1	CYP3A5	ENSGALP00000055162	ENSGALP00000007068	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.522
CYP3A5	CYP1A1	ENSGALP00000007068	ENSGALP00000039219	Uncharacterized protein.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.970
CYP3A5	CYP1A2	ENSGALP00000007068	ENSGALP00000002016	Uncharacterized protein.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.973
CYP3A5	CYP1B1	ENSGALP00000007068	ENSGALP00000048510	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.500
CYP3A5	CYP1C1	ENSGALP00000007068	ENSGALP00000055162	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.522
GPX1	GPX4	ENSGALP00000041423	ENSGALP00000069197	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.884
GPX1	GPX7	ENSGALP00000041423	ENSGALP00000017282	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.420
GPX1	SOD2	ENSGALP00000041423	ENSGALP00000019039	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.802
GPX4	GPX1	ENSGALP00000069197	ENSGALP00000041423	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.884
GPX4	SOD2	ENSGALP00000069197	ENSGALP00000019039	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.772
GPX7	GPX1	ENSGALP00000017282	ENSGALP00000041423	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.420