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RHO RHO PXDN PXDN NMBR NMBR NPY NPY TACR3 TACR3 NEFH NEFH PGK2 PGK2 OPN1MSW OPN1MSW TRPV1 TRPV1 NPR1 NPR1 ACTB ACTB SLC17A6 SLC17A6 TACR1 TACR1 NMB NMB PXDNL PXDNL PAX2 PAX2 GRPR GRPR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RHORhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (351 aa)
PXDNPeroxidasin. (1611 aa)
NMBRNeuromedin-B receptor; Belongs to the G-protein coupled receptor 1 family. (388 aa)
NPYC-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (439 aa)
NEFHNeurofilament heavy; Belongs to the intermediate filament family. (947 aa)
PGK2Phosphoglycerate kinase; Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3- diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility. (417 aa)
OPN1MSWGreen-sensitive opsin; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (355 aa)
TRPV1ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (843 aa)
NPR1Guanylate cyclase. (835 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
SLC17A6MFS domain-containing protein. (585 aa)
TACR1Substance P receptor; Belongs to the G-protein coupled receptor 1 family. (411 aa)
NMBUncharacterized protein. (159 aa)
PXDNLUncharacterized protein. (1406 aa)
PAX2Paired-box containing protein Pax-2. (394 aa)
GRPRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (387 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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