4 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RBX1	RING-type domain-containing protein. (108 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	CACUL1	Cullin domain-containing protein; Belongs to the cullin family. (377 aa)
	SKP1	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity). (163 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACUL1	RBX1	ENSGALP00000055119	ENSGALP00000019539	Cullin domain-containing protein; Belongs to the cullin family.	RING-type domain-containing protein.	0.709
CACUL1	SKP1	ENSGALP00000055119	ENSGALP00000010447	Cullin domain-containing protein; Belongs to the cullin family.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.817
CUL1	RBX1	ENSGALP00000046909	ENSGALP00000019539	Cullin 1; Belongs to the cullin family.	RING-type domain-containing protein.	0.999
CUL1	SKP1	ENSGALP00000046909	ENSGALP00000010447	Cullin 1; Belongs to the cullin family.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.999
RBX1	CACUL1	ENSGALP00000019539	ENSGALP00000055119	RING-type domain-containing protein.	Cullin domain-containing protein; Belongs to the cullin family.	0.709
RBX1	CUL1	ENSGALP00000019539	ENSGALP00000046909	RING-type domain-containing protein.	Cullin 1; Belongs to the cullin family.	0.999
RBX1	SKP1	ENSGALP00000019539	ENSGALP00000010447	RING-type domain-containing protein.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.999
SKP1	CACUL1	ENSGALP00000010447	ENSGALP00000055119	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	Cullin domain-containing protein; Belongs to the cullin family.	0.817
SKP1	CUL1	ENSGALP00000010447	ENSGALP00000046909	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	Cullin 1; Belongs to the cullin family.	0.999
SKP1	RBX1	ENSGALP00000010447	ENSGALP00000019539	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	RING-type domain-containing protein.	0.999