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CACUL1 | Cullin domain-containing protein; Belongs to the cullin family. (377 aa) | ||||
LPO | Uncharacterized protein. (790 aa) | ||||
HMGB1 | High mobility group protein B1; Multifunctional redox sensitive protein with various roles in different cellular compartments. Nuclear functions are attributed to fully reduced HGMB1. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA, DNA-containing cruciforms or bent structures, supercoiled DNA and ZDNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Can restructure the canonical nucleosome. Proposed to be an universal biosensor for nucle [...] (215 aa) | ||||
NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1402 aa) | ||||
FYN | Tyrosine-protein kinase Fyn; Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling. (589 aa) | ||||
GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa) | ||||
NCK1 | Cytoplasmic protein. (380 aa) | ||||
SMARCA4 | Uncharacterized protein. (1178 aa) | ||||
KRT14 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5- KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. (467 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog 3; Transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinase. SMAD3 is a receptor- regulated SMAD (R-SMAD) (By similarity). (426 aa) | ||||
KRT17 | IF rod domain-containing protein; Belongs to the intermediate filament family. (559 aa) | ||||
NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1435 aa) | ||||
PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (652 aa) | ||||
NR3C1 | Uncharacterized protein. (837 aa) | ||||
COL3A1 | Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. (1460 aa) | ||||
SIRT1 | Deacetylase sirtuin-type domain-containing protein. (881 aa) | ||||
UGT1A1 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa) | ||||
CUL3 | Cullin 3; Belongs to the cullin family. (768 aa) | ||||
GPX7 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa) | ||||
CRYZ | PKS_ER domain-containing protein. (331 aa) | ||||
SOD2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa) | ||||
UGT2A1 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa) | ||||
IL2 | Interleukin; Belongs to the IL-15/IL-21 family. (143 aa) | ||||
RBX1 | RING-type domain-containing protein. (108 aa) | ||||
MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (63 aa) | ||||
BACH1 | BTB domain and CNC homolog 1. (675 aa) | ||||
GCLC | Glutamate-cysteine ligase catalytic subunit. (636 aa) | ||||
HMOX1 | Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. (317 aa) | ||||
GPX8 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa) | ||||
GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (182 aa) | ||||
MT4 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals; Belongs to the metallothionein superfamily. Type 1 family. (63 aa) | ||||
CAV1 | Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa) | ||||
SIRT2 | Deacetylase sirtuin-type domain-containing protein. (485 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (755 aa) | ||||
CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) | ||||
IL1B | Interleukin-1; Belongs to the IL-1 family. (267 aa) |