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| | AGRP | Agouti-related protein. (233 aa) |
| | CHRNA3 | Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (496 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling. Controls somitogenesis by sequestering the BMP-4 activity which in turn differentiates distinct subtypes of the mesoderm along the mediolateral axis. (387 aa) |
| | SPARC | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity). (298 aa) |
| | GDAP1L1 | Ganglioside induced differentiation associated protein 1 like 1. (367 aa) |
| | ARNTL | Aryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] (633 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | ADIPOQ | C1q domain-containing protein. (244 aa) |
| | CSF1R | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa) |
| | BTBD8 | BTB domain containing 8. (1780 aa) |
| | VIPR2 | VPAC2 receptor; Belongs to the G-protein coupled receptor 2 family. (439 aa) |
| | FTH1 | Ferritin heavy chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). (180 aa) |
| | SST | Somatostatin-14; Somatostatin inhibits the release of somatotropin. (116 aa) |
| | DRD2 | Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa) |
| | IL18 | Interleukin-18; Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. (198 aa) |
| | GPR22 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (433 aa) |
| | SNAP25 | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa) |
| | GFRA1 | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity). (469 aa) |
| | LOC417800 | Uncharacterized protein. (225 aa) |
| | SSTR1 | Somatostatin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (392 aa) |
| | LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (909 aa) |
| | SLC29A1 | Solute carrier family 29 member 1 (Augustine blood group). (282 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (386 aa) |
| | SLC29A4 | Solute carrier family 29 member 4. (527 aa) |
| | EML5 | EMAP like 5. (1969 aa) |
| | CHRM3 | Muscarinic acetylcholine receptor M3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. (639 aa) |
| | NPY | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa) |
| | SCN3A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1995 aa) |
| | SCTR | Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (449 aa) |
| | SOX10 | Transcription factor SOX-10; Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. (461 aa) |
| | CSF2RB | Uncharacterized protein. (678 aa) |
| | SLC28A3 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (684 aa) |
| | PRL | Prolactin. (229 aa) |
| | MTNR1A | Melatonin receptor type 1A; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). (353 aa) |
| | SCGN | Secretagogin, EF-hand calcium binding protein. (273 aa) |
| | OPRM1 | Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (415 aa) |
| | LAMA4 | Laminin subunit alpha 4. (1827 aa) |
| | OPRK1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa) |
| | TAGLN3 | Transgelin; Belongs to the calponin family. (199 aa) |
| | GRIK2 | Glutamate ionotropic receptor kainate type subunit 2. (917 aa) |
| | DSCAM | Down syndrome cell adhesion molecule homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self- avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (By similarity). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor [...] (2034 aa) |
| | IL17A | Uncharacterized protein. (169 aa) |
| | SLC5A7 | Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (578 aa) |
| | RASA3 | Uncharacterized protein. (836 aa) |
| | NR1D2 | Uncharacterized protein. (587 aa) |
| | NMU | Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family. (181 aa) |
| | LEPR | Uncharacterized protein. (1148 aa) |
| | PLA2R1 | Uncharacterized protein. (1459 aa) |
| | EDNRB | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (560 aa) |
| | PHOX2B | Paired like homeobox 2B. (292 aa) |
| | BMPR1B | Bone morphogenetic protein receptor type-1B; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptiona (By similarity). Positively regulates chondrocyte differentiation. (502 aa) |
| | ADRA2A | Adrenoceptor alpha 2A. (444 aa) |
| | ASS1 | Argininosuccinate synthase; One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues; Belongs to the argininosuccinate synthase family. (416 aa) |
| | CHRNB4 | Neuronal acetylcholine receptor subunit beta-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (489 aa) |
| | GRPR | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (387 aa) |
| | NTS | Neurotensin. (164 aa) |
| | CCR10 | C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | CALB2 | Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons. (311 aa) |
| | TUBB2A | Tubulin beta-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (445 aa) |
| | GAL | Galanin variant 1. (141 aa) |
| | CXCR7 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | ECE1 | Endothelin converting enzyme-1. (752 aa) |
| | GPM6B | Uncharacterized protein. (318 aa) |
| | SCG2 | Secretogranin II. (629 aa) |
| | FOXP1 | Forkhead box protein P1; Transcriptional repressor. (686 aa) |
| | CCK | Cholecystokinin-70; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear (By similarity). It also decreases food intake and regulates gastrointestinal physiological processes. (130 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (662 aa) |
| | CRMP1 | Collapsin response mediator protein-1A. (683 aa) |
| | EGF | Uncharacterized protein. (1283 aa) |
| | GUCY1A1 | Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa) |
| | PER2 | Period circadian protein homolog 2; Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardi [...] (1345 aa) |
| | CXCL12 | SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (167 aa) |
| | SCT | Secretin. (157 aa) |
| | OPRD1 | Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | TEF | Transcription factor VBP; Transcription factor that binds to and transactivates the vitellogenin II (VTG2) promoter. Binds to the palindromic sequence 5'- GTTTACATAAAC-3'; Belongs to the bZIP family. PAR subfamily. (319 aa) |
| | RSPO3 | Uncharacterized protein. (275 aa) |
| | HTR3A | Neur_chan_memb domain-containing protein. (209 aa) |
| | NFIA | Nuclear factor 1 A-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (582 aa) |
| | DAGLA | Diacylglycerol lipase alpha. (1025 aa) |
| | GABRB3 | Gamma-aminobutyric acid receptor subunit beta-3; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA- gated ion channel (By similarity). (476 aa) |
| | SYT4 | Synaptotagmin 4. (425 aa) |
| | GRID1 | Glutamate ionotropic receptor delta type subunit 1. (928 aa) |
| | ERBB3 | Protein kinase domain-containing protein. (1319 aa) |
| | TUBB3 | Tubulin beta-4 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain; Belongs to the tubulin family. (496 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. Activated KIT also transmits signals via [...] (960 aa) |
| | JAZF1 | Uncharacterized protein. (243 aa) |
| | PDPN | Uncharacterized protein. (146 aa) |
| | IL7 | Interleukin-7. (146 aa) |
| | GLP2R | Glucagon-like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (529 aa) |
| | NRXN1 | Neurexin-1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. (1503 aa) |
| | CCKAR | Cholecystokinin type 1 receptor; Belongs to the G-protein coupled receptor 1 family. (429 aa) |
| | NID1 | Nidogen 1. (1153 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1021 aa) |
| | GRIA3 | Uncharacterized protein. (888 aa) |
| | DGKB | Diacylglycerol kinase. (814 aa) |
| | ETV1 | Ets domain protein. (477 aa) |
| | GLS2 | ANK_REP_REGION domain-containing protein. (667 aa) |
| | COLQ | Collagen like tail subunit of asymmetric acetylcholinesterase. (298 aa) |
| | GAD2 | Glutamate decarboxylase 2. (807 aa) |
| | PTPRZ1 | Protein-tyrosine-phosphatase. (2343 aa) |
| | PIEZO2 | Piezo-type mechanosensitive ion channel component. (2833 aa) |
| | CALCA | Calcitonin; Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. (138 aa) |
| | CNTNAP2 | Contactin associated protein like 2. (1344 aa) |
| | EDN3 | Endothelin 3. (151 aa) |
| | NR5A2 | Nuclear receptor subfamily 5 group A member 2; Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism (By similarity). Activates the transcription of CYP2C38 (By similarity). (541 aa) |
| | ELAVL4 | ELAV-like protein; Belongs to the RRM elav family. (402 aa) |
| | CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | NDFIP1 | Nedd4 family interacting protein 1. (213 aa) |
| | GAS7 | Growth arrest specific 7. (474 aa) |
| | ADM | Uncharacterized protein. (73 aa) |
| | IL13RA1 | Interleukin 13 receptor subunit alpha 1. (424 aa) |
| | PYY | Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. (90 aa) |
| | CD8A-2 | Ig-like domain-containing protein. (235 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa) |
| | UCHL1 | Ubiquitin carboxyl-terminal hydrolase. (224 aa) |
| | FABP7 | Fatty acid-binding protein, brain; FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | TPH1 | Tryptophan 5-hydroxylase 1; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. (475 aa) |
| | TAC1 | Tachykinin precursor 1. (114 aa) |
| | CHGB | Chromogranin B. (673 aa) |
| | CSF1 | Uncharacterized protein. (493 aa) |
| | ANO1 | Anoctamin. (1020 aa) |
| | IL12RB1 | Fibronectin type-III domain-containing protein. (591 aa) |
| | POSTN | Uncharacterized protein. (857 aa) |
| | NRCAM | Neuronal cell adhesion molecule; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Specifically involved in the development of optic fibres in the retina; Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. (1836 aa) |
| | GCGR | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (532 aa) |
| | SNCA | Alpha-synuclein; Belongs to the synuclein family. (143 aa) |
| | GFRA2 | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (By similarity); Belongs to the GDNFR family. (535 aa) |
| | FST | Follistatin; Binds directly to activin and functions as an activin antagonist. Inhibits activin A signaling in the iris and regulates somatostatin phenotype in ciliary ganglion neurons. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). (320 aa) |
| | STMN3 | Stathmin-3; Belongs to the stathmin family. (249 aa) |
| | SLC29A3 | Solute carrier family 29 member 3. (458 aa) |
| | GRM7 | Glutamate metabotropic receptor 7. (1163 aa) |
| | ANK2 | Ankyrin 2. (3970 aa) |
| | ADCYAP1R1 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (499 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (488 aa) |
| | CD8A-3 | Ig-like domain-containing protein. (318 aa) |
| | WNT1 | Protein Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. Developmental protein that promotes cell proliferation in the developing spinal cord. Has a role in osteoblast function, bone development and bone homeostasis (By similarity). (550 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (254 aa) |
| | CASZ1 | Castor zinc finger 1. (1967 aa) |
| | DLG2 | Guanylate kinase-like domain-containing protein. (182 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily. (831 aa) |
| | ACHE | Acetylcholinesterase; Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft; Belongs to the type-B carboxylesterase/lipase family. (767 aa) |
| | DCTN1 | Dynactin subunit 1; Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Plays a role in metaphase spindle orientation. (1349 aa) |
| | ADIPOR1 | Uncharacterized protein. (479 aa) |
| | PLP1 | Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin; Belongs to the myelin proteolipid protein family. (277 aa) |
| | PER3 | PAS domain-containing protein. (1182 aa) |
