5 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDH1	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. E-cadherin is a ligand for integrin alpha- E/beta-7. (887 aa)
	APOA1	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. (264 aa)
	TTR	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (168 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
	LOC112531842	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOA1	LOC112531842	ENSGALP00000011510	ENSGALP00000063278	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.807
APOA1	TTR	ENSGALP00000011510	ENSGALP00000024388	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.806
B2M	TTR	ENSGALP00000039454	ENSGALP00000024388	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.429
LOC112531842	APOA1	ENSGALP00000063278	ENSGALP00000011510	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	0.807
LOC112531842	TTR	ENSGALP00000063278	ENSGALP00000024388	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.807
TTR	APOA1	ENSGALP00000024388	ENSGALP00000011510	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	0.806
TTR	B2M	ENSGALP00000024388	ENSGALP00000039454	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.429
TTR	LOC112531842	ENSGALP00000024388	ENSGALP00000063278	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.	0.807