(10 nodes) (2021) Ambient Light Regulates Retinal Dopamine Signaling and Myopia Susceptibility. network (Gallus gallus)

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Your Input:
	LOC769866	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (208 aa)
	OPN4	G_PROTEIN_RECEP_F1_2 domain-containing protein. (528 aa)
	HPRT1	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (330 aa)
	EGR1	Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (510 aa)
	PRTFDC1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (226 aa)
	MAOA	Amine oxidase. (532 aa)
	PXDN	Peroxidasin. (1611 aa)
	PXDNL	Uncharacterized protein. (1406 aa)
	TH	Tyrosine hydroxylase. (491 aa)
	MAOB	Amine oxidase. (521 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGR1	OPN4	ENSGALP00000012417	ENSGALP00000002985	Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...]	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.691
HPRT1	LOC769866	ENSGALP00000009829	ENSGALP00000008592	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.901
HPRT1	PXDN	ENSGALP00000009829	ENSGALP00000026363	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	Peroxidasin.	0.550
HPRT1	PXDNL	ENSGALP00000009829	ENSGALP00000049777	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	Uncharacterized protein.	0.550
HPRT1	TH	ENSGALP00000009829	ENSGALP00000051175	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	Tyrosine hydroxylase.	0.471
LOC769866	HPRT1	ENSGALP00000008592	ENSGALP00000009829	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.901
MAOA	MAOB	ENSGALP00000026110	ENSGALP00000052475	Amine oxidase.	Amine oxidase.	0.902
MAOA	TH	ENSGALP00000026110	ENSGALP00000051175	Amine oxidase.	Tyrosine hydroxylase.	0.732
MAOB	MAOA	ENSGALP00000052475	ENSGALP00000026110	Amine oxidase.	Amine oxidase.	0.902
MAOB	TH	ENSGALP00000052475	ENSGALP00000051175	Amine oxidase.	Tyrosine hydroxylase.	0.732
OPN4	EGR1	ENSGALP00000002985	ENSGALP00000012417	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...]	0.691
OPN4	TH	ENSGALP00000002985	ENSGALP00000051175	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Tyrosine hydroxylase.	0.537
PXDN	HPRT1	ENSGALP00000026363	ENSGALP00000009829	Peroxidasin.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.550
PXDN	PXDNL	ENSGALP00000026363	ENSGALP00000049777	Peroxidasin.	Uncharacterized protein.	0.696
PXDN	TH	ENSGALP00000026363	ENSGALP00000051175	Peroxidasin.	Tyrosine hydroxylase.	0.725
PXDNL	HPRT1	ENSGALP00000049777	ENSGALP00000009829	Uncharacterized protein.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.550
PXDNL	PXDN	ENSGALP00000049777	ENSGALP00000026363	Uncharacterized protein.	Peroxidasin.	0.696
PXDNL	TH	ENSGALP00000049777	ENSGALP00000051175	Uncharacterized protein.	Tyrosine hydroxylase.	0.726
TH	HPRT1	ENSGALP00000051175	ENSGALP00000009829	Tyrosine hydroxylase.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.471
TH	MAOA	ENSGALP00000051175	ENSGALP00000026110	Tyrosine hydroxylase.	Amine oxidase.	0.732