STRINGSTRING
CPAMD8 CPAMD8 LTBP2 LTBP2 IGFBP1 IGFBP1 CYP7A1 CYP7A1 GRHL3 GRHL3 COL3A1 COL3A1 CYP1B1 CYP1B1 PITX2 PITX2 HSD11B2 HSD11B2 WNT9B WNT9B CYP1A1 CYP1A1 WDR35 WDR35 MYOC MYOC GUCA1C GUCA1C TYR TYR DSG2 DSG2 CDK6 CDK6 CYP1A2 CYP1A2 GPATCH3 GPATCH3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPAMD8C3 and PZP like alpha-2-macroglobulin domain containing 8. (1857 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1851 aa)
IGFBP1Uncharacterized protein. (269 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa)
GRHL3Grainyhead like transcription factor 3. (629 aa)
COL3A1Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. (1460 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
PITX2Pituitary homeobox 2; May play an important role in development and maintenance of anterior structures. May play a role in determining left-right asymmetry and in vasculogenesis during avian embryogenesis. (333 aa)
HSD11B2Hydroxysteroid 11-beta dehydrogenase 2. (349 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
CYP1A1Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
WDR35WD repeat-containing protein 35. (1178 aa)
MYOCMyocilin. (467 aa)
GUCA1CGuanylate cyclase activator 1C. (209 aa)
TYRTyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. (537 aa)
DSG2Desmoglein 2. (1097 aa)
CDK6Cyclin-dependent kinase; Belongs to the protein kinase superfamily. (326 aa)
CYP1A2Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
GPATCH3G-patch domain-containing protein. (493 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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