9 items (Gallus gallus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	CACUL1	Cullin domain-containing protein; Belongs to the cullin family. (377 aa)
	CDK9	Cyclin-dependent kinase 9; Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P- TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity). Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (484 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (409 aa)
	JUN	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. May be involved in activated KRAS-mediated transcriptional activation of USP28. May bind to the USP28 promoter; Belongs to the bZIP family. Jun subfamily. (310 aa)
	ALB	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family. (565 aa)
	SKP1	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity). (163 aa)
	RBX1	RING-type domain-containing protein. (108 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	JUN	ENSGALP00000044604	ENSGALP00000037247	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. May be involved in activated KRAS-mediated transcriptional activation of USP28. May bind to the USP28 promoter; Belongs to the bZIP family. Jun subfamily.	0.427
AURKA	CUL1	ENSGALP00000032883	ENSGALP00000046909	Aurora kinase A; Belongs to the protein kinase superfamily.	Cullin 1; Belongs to the cullin family.	0.627
AURKA	PCNA	ENSGALP00000032883	ENSGALP00000064149	Aurora kinase A; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.429
AURKA	RBX1	ENSGALP00000032883	ENSGALP00000019539	Aurora kinase A; Belongs to the protein kinase superfamily.	RING-type domain-containing protein.	0.553
AURKA	SKP1	ENSGALP00000032883	ENSGALP00000010447	Aurora kinase A; Belongs to the protein kinase superfamily.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.637
CACUL1	RBX1	ENSGALP00000055119	ENSGALP00000019539	Cullin domain-containing protein; Belongs to the cullin family.	RING-type domain-containing protein.	0.709
CACUL1	SKP1	ENSGALP00000055119	ENSGALP00000010447	Cullin domain-containing protein; Belongs to the cullin family.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.817
CUL1	AURKA	ENSGALP00000046909	ENSGALP00000032883	Cullin 1; Belongs to the cullin family.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.627
CUL1	RBX1	ENSGALP00000046909	ENSGALP00000019539	Cullin 1; Belongs to the cullin family.	RING-type domain-containing protein.	0.999
CUL1	SKP1	ENSGALP00000046909	ENSGALP00000010447	Cullin 1; Belongs to the cullin family.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.999
JUN	ALB	ENSGALP00000037247	ENSGALP00000044604	Transcription factor AP-1; Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. May be involved in activated KRAS-mediated transcriptional activation of USP28. May bind to the USP28 promoter; Belongs to the bZIP family. Jun subfamily.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	0.427
PCNA	AURKA	ENSGALP00000064149	ENSGALP00000032883	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.429
PCNA	RBX1	ENSGALP00000064149	ENSGALP00000019539	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	RING-type domain-containing protein.	0.548
RBX1	AURKA	ENSGALP00000019539	ENSGALP00000032883	RING-type domain-containing protein.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.553
RBX1	CACUL1	ENSGALP00000019539	ENSGALP00000055119	RING-type domain-containing protein.	Cullin domain-containing protein; Belongs to the cullin family.	0.709
RBX1	CUL1	ENSGALP00000019539	ENSGALP00000046909	RING-type domain-containing protein.	Cullin 1; Belongs to the cullin family.	0.999
RBX1	PCNA	ENSGALP00000019539	ENSGALP00000064149	RING-type domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.548
RBX1	SKP1	ENSGALP00000019539	ENSGALP00000010447	RING-type domain-containing protein.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	0.999
SKP1	AURKA	ENSGALP00000010447	ENSGALP00000032883	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	Aurora kinase A; Belongs to the protein kinase superfamily.	0.637
SKP1	CACUL1	ENSGALP00000010447	ENSGALP00000055119	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity).	Cullin domain-containing protein; Belongs to the cullin family.	0.817