| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C9orf72 | TARDBP | ENSGALP00000002890 | ENSGALP00000004576 | C9orf72-SMCR8 complex subunit. | TAR DNA-binding protein 43; Probably involved in transcriptional repression (By similarity). May play a role in the maintenance of the circadian clock periodicity (By similarity). | 0.989 |
| C9orf72 | TMEM106B | ENSGALP00000002890 | ENSGALP00000056588 | C9orf72-SMCR8 complex subunit. | Uncharacterized protein. | 0.741 |
| CALB1 | CUX1 | ENSGALP00000056213 | ENSGALP00000002788 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | CASP_C domain-containing protein. | 0.509 |
| CALB1 | GAPDH | ENSGALP00000056213 | ENSGALP00000063325 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.523 |
| CALB1 | GFAP | ENSGALP00000056213 | ENSGALP00000001335 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.851 |
| CALB1 | MBP | ENSGALP00000056213 | ENSGALP00000065604 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.522 |
| CALB1 | OLIG2 | ENSGALP00000056213 | ENSGALP00000047462 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Oligodendrocyte transcription factor 2; Required for oligodendrocyte and motor neuron specification in the spinal cord. | 0.603 |
| CALB1 | PAX2 | ENSGALP00000056213 | ENSGALP00000045193 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Paired-box containing protein Pax-2. | 0.596 |
| CALB1 | PVALB | ENSGALP00000056213 | ENSGALP00000047809 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Parvalbumin, muscle; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity); Belongs to the parvalbumin family. | 0.982 |
| CTSD | CTSS | ENSGALP00000010662 | ENSGALP00000065590 | Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. In chicken it is a key enzyme for yolk formation as it is capable of catalyzing intra oocytic break down of protein components of both vitellogenin and VLDL. | Uncharacterized protein; Belongs to the peptidase C1 family. | 0.893 |
| CTSD | GAPDH | ENSGALP00000010662 | ENSGALP00000063325 | Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. In chicken it is a key enzyme for yolk formation as it is capable of catalyzing intra oocytic break down of protein components of both vitellogenin and VLDL. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.490 |
| CTSD | LAMP1 | ENSGALP00000010662 | ENSGALP00000052871 | Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. In chicken it is a key enzyme for yolk formation as it is capable of catalyzing intra oocytic break down of protein components of both vitellogenin and VLDL. | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis; Belongs to the LAMP family. | 0.903 |
| CTSD | LAMP2 | ENSGALP00000010662 | ENSGALP00000068184 | Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. In chicken it is a key enzyme for yolk formation as it is capable of catalyzing intra oocytic break down of protein components of both vitellogenin and VLDL. | Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Functions by binding target proteins, such as GAPDH and MLLT11, and targeting them for lysosomal degradation (By similarity). Plays a role in lysosomal protein degradation in response to starvation (By similarity). Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express [...] | 0.715 |
| CTSS | CTSD | ENSGALP00000065590 | ENSGALP00000010662 | Uncharacterized protein; Belongs to the peptidase C1 family. | Cathepsin D heavy chain; Acid protease active in intracellular protein breakdown. In chicken it is a key enzyme for yolk formation as it is capable of catalyzing intra oocytic break down of protein components of both vitellogenin and VLDL. | 0.893 |
| CTSS | LAMP1 | ENSGALP00000065590 | ENSGALP00000052871 | Uncharacterized protein; Belongs to the peptidase C1 family. | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis; Belongs to the LAMP family. | 0.784 |
| CTSS | LAMP2 | ENSGALP00000065590 | ENSGALP00000068184 | Uncharacterized protein; Belongs to the peptidase C1 family. | Lysosome-associated membrane glycoprotein 2; Plays an important role in chaperone-mediated autophagy, a process that mediates lysosomal degradation of proteins in response to various stresses and as part of the normal turnover of proteins with a long biological half-live. Functions by binding target proteins, such as GAPDH and MLLT11, and targeting them for lysosomal degradation (By similarity). Plays a role in lysosomal protein degradation in response to starvation (By similarity). Required for the fusion of autophagosomes with lysosomes during autophagy. Cells that lack LAMP2 express [...] | 0.629 |
| CTSS | MBP | ENSGALP00000065590 | ENSGALP00000065604 | Uncharacterized protein; Belongs to the peptidase C1 family. | Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity). | 0.449 |
| CUX1 | CALB1 | ENSGALP00000002788 | ENSGALP00000056213 | CASP_C domain-containing protein. | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | 0.509 |
| CUX1 | GFAP | ENSGALP00000002788 | ENSGALP00000001335 | CASP_C domain-containing protein. | Glial fibrillary acidic protein; Belongs to the intermediate filament family. | 0.703 |
| CUX1 | OLIG2 | ENSGALP00000002788 | ENSGALP00000047462 | CASP_C domain-containing protein. | Oligodendrocyte transcription factor 2; Required for oligodendrocyte and motor neuron specification in the spinal cord. | 0.582 |