12 items (Gallus gallus) - STRING interaction network

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Your Input:
	MITF	BHLH domain-containing protein. (519 aa)
	COL3A1	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. (1460 aa)
	NFATC3	Nuclear factor of activated T cells 3. (1121 aa)
	PRKACB	Uncharacterized protein; Belongs to the protein kinase superfamily. (398 aa)
	TYRP1	5,6-dihydroxyindole-2-carboxylic acid oxidase; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. (536 aa)
	OVAL	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white. (386 aa)
	TGFB2	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (412 aa)
	TYR	Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. (537 aa)
	DYRK1A	Protein kinase domain-containing protein. (756 aa)
	OPN3	Opsin 3. (395 aa)
	CTRB2	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
	MC1R	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family. (314 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL3A1	CTRB2	ENSGALP00000051057	ENSGALP00000000050	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.678
COL3A1	OVAL	ENSGALP00000051057	ENSGALP00000036403	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	0.754
COL3A1	PRKACB	ENSGALP00000051057	ENSGALP00000041979	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.533
COL3A1	TGFB2	ENSGALP00000051057	ENSGALP00000031309	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...]	0.792
COL3A1	TYR	ENSGALP00000051057	ENSGALP00000027812	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.	0.400
CTRB2	COL3A1	ENSGALP00000000050	ENSGALP00000051057	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.678
CTRB2	OVAL	ENSGALP00000000050	ENSGALP00000036403	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	0.640
MC1R	MITF	ENSGALP00000071620	ENSGALP00000070157	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	BHLH domain-containing protein.	0.863
MC1R	TYR	ENSGALP00000071620	ENSGALP00000027812	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.	0.919
MC1R	TYRP1	ENSGALP00000071620	ENSGALP00000037537	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	5,6-dihydroxyindole-2-carboxylic acid oxidase; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.	0.904
MITF	MC1R	ENSGALP00000070157	ENSGALP00000071620	BHLH domain-containing protein.	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	0.863
MITF	OPN3	ENSGALP00000070157	ENSGALP00000017480	BHLH domain-containing protein.	Opsin 3.	0.404
MITF	TYR	ENSGALP00000070157	ENSGALP00000027812	BHLH domain-containing protein.	Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.	0.975
MITF	TYRP1	ENSGALP00000070157	ENSGALP00000037537	BHLH domain-containing protein.	5,6-dihydroxyindole-2-carboxylic acid oxidase; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.	0.876
OPN3	MITF	ENSGALP00000017480	ENSGALP00000070157	Opsin 3.	BHLH domain-containing protein.	0.404
OVAL	COL3A1	ENSGALP00000036403	ENSGALP00000051057	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.754
OVAL	CTRB2	ENSGALP00000036403	ENSGALP00000000050	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.640
PRKACB	COL3A1	ENSGALP00000041979	ENSGALP00000051057	Uncharacterized protein; Belongs to the protein kinase superfamily.	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.533
TGFB2	COL3A1	ENSGALP00000031309	ENSGALP00000051057	Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...]	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.792
TYR	COL3A1	ENSGALP00000027812	ENSGALP00000051057	Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.400