20 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	HBS1L	HBS1 like translational GTPase. (728 aa)
	BCL11A	Uncharacterized protein. (796 aa)
	CCR5	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	VAMP4	Vesicle associated membrane protein 4. (141 aa)
	MYB	Transcriptional activator Myb; Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. (785 aa)
	LMO2	LIM domain only 2. (216 aa)
	ALB	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family. (565 aa)
	ALK	Tyrosine-protein kinase receptor. (616 aa)
	DMD	Dystrophin; May play a role in anchoring the cytoskeleton to the plasma membrane. (3700 aa)
	EML4	EMAP like 4. (1021 aa)
	CD34	CD34 molecule. (385 aa)
	SOX6	HMG box domain-containing protein. (817 aa)
	HPRT1	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity). (330 aa)
	PLK1	Serine/threonine-protein kinase PLK. (595 aa)
	HMGA2	High mobility group protein I-C. (109 aa)
	KITLG	Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). (287 aa)
	CXCR4	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	HBBA	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. The beta chain is a component of adult hemoglobin A and D. (147 aa)
	CSF3	Myelomonocytic growth factor; Hematopoietic growth factor that stimulates the proliferation and colony formation of normal and transformed avian cells of the myeloid lineage; Belongs to the IL-6 superfamily. (201 aa)
	THPO	Thrombopoietin. (177 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CCR5	ENSGALP00000044604	ENSGALP00000053031	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.499
ALB	CD34	ENSGALP00000044604	ENSGALP00000001784	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	CD34 molecule.	0.725
ALB	CSF3	ENSGALP00000044604	ENSGALP00000044330	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Myelomonocytic growth factor; Hematopoietic growth factor that stimulates the proliferation and colony formation of normal and transformed avian cells of the myeloid lineage; Belongs to the IL-6 superfamily.	0.448
ALB	CXCR4	ENSGALP00000044604	ENSGALP00000020157	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.594
ALB	DMD	ENSGALP00000044604	ENSGALP00000071548	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Dystrophin; May play a role in anchoring the cytoskeleton to the plasma membrane.	0.411
ALB	HPRT1	ENSGALP00000044604	ENSGALP00000009829	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Hypoxanthine-guanine phosphoribosyltransferase; Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5- phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).	0.585
ALB	KITLG	ENSGALP00000044604	ENSGALP00000018246	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity).	0.476
ALK	EML4	ENSGALP00000070314	ENSGALP00000073091	Tyrosine-protein kinase receptor.	EMAP like 4.	0.878
BCL11A	CD34	ENSGALP00000054060	ENSGALP00000001784	Uncharacterized protein.	CD34 molecule.	0.533
BCL11A	HBBA	ENSGALP00000054060	ENSGALP00000035593	Uncharacterized protein.	Hemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. The beta chain is a component of adult hemoglobin A and D.	0.732
BCL11A	HBS1L	ENSGALP00000054060	ENSGALP00000055222	Uncharacterized protein.	HBS1 like translational GTPase.	0.797
BCL11A	HMGA2	ENSGALP00000054060	ENSGALP00000016038	Uncharacterized protein.	High mobility group protein I-C.	0.459
BCL11A	LMO2	ENSGALP00000054060	ENSGALP00000045476	Uncharacterized protein.	LIM domain only 2.	0.563
BCL11A	SOX6	ENSGALP00000054060	ENSGALP00000009790	Uncharacterized protein.	HMG box domain-containing protein.	0.761
CCR5	ALB	ENSGALP00000053031	ENSGALP00000044604	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	0.499
CCR5	CD34	ENSGALP00000053031	ENSGALP00000001784	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	CD34 molecule.	0.634
CCR5	CXCR4	ENSGALP00000053031	ENSGALP00000020157	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.766
CD34	ALB	ENSGALP00000001784	ENSGALP00000044604	CD34 molecule.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	0.725
CD34	BCL11A	ENSGALP00000001784	ENSGALP00000054060	CD34 molecule.	Uncharacterized protein.	0.533
CD34	CCR5	ENSGALP00000001784	ENSGALP00000053031	CD34 molecule.	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.634