STRINGSTRING
NUCB2 NUCB2 GALR1 GALR1 GAL GAL CCK CCK CRH CRH UCN3 UCN3 PYY PYY C12orf29 C12orf29 POMC POMC APLN APLN GALR2 GALR2 AGRP AGRP INS INS NPY NPY FSHB FSHB GALR3 GALR3 SPX SPX DEFB4A DEFB4A MRPS26 MRPS26 NPVF NPVF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUCB2Uncharacterized protein. (455 aa)
GALR1Galanin receptor; Belongs to the G-protein coupled receptor 1 family. (357 aa)
GALGalanin variant 1. (141 aa)
CCKCholecystokinin-70; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear (By similarity). It also decreases food intake and regulates gastrointestinal physiological processes. (130 aa)
CRHCorticotropin releasing hormone. (167 aa)
UCN3Urocortin 3. (154 aa)
PYYPeptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. (90 aa)
C12orf29Chromosome 12 open reading frame 29. (324 aa)
POMCUncharacterized protein. (251 aa)
APLNApelin. (78 aa)
GALR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (371 aa)
AGRPAgouti-related protein. (233 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (107 aa)
NPYC-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa)
FSHBFollicle stimulating hormone, beta polypeptide. (131 aa)
GALR3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (405 aa)
SPXSpexin hormone. (116 aa)
DEFB4AGallinacin-2; Potent antibacterial activity against the Gram-negative bacterium E.coli ML-35, and against the Gram-positive bacterium L.monocytogenes EGD. Lacks antifungal activity against C.albicans. (64 aa)
MRPS2628S ribosomal protein S26, mitochondrial. (298 aa)
NPVFGonadotropin-inhibitory hormone. (173 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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