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SPRY3 | Sprouty-like protein 3. (291 aa) | ||||
SLC25A5 | Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (389 aa) | ||||
SLC25A43 | Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family. (339 aa) | ||||
SLC16A7 | MFS domain-containing protein. (480 aa) | ||||
KITLG | Processed kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Acts synergistically with other cytokines, probably interleukins (By similarity). (287 aa) | ||||
IRF4 | Interferon regulatory factor 4. (445 aa) | ||||
OCA2 | OCA2 melanosomal transmembrane protein. (726 aa) | ||||
TYR | Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. (537 aa) | ||||
UCP3 | Mitochondrial uncoupling protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) | ||||
EDNRB | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (560 aa) | ||||
DCT | L-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (521 aa) | ||||
SLC25A6 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) | ||||
TYRP1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. (536 aa) | ||||
SLC25A20 | Solute carrier family 25 member 20; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa) | ||||
FOXP1 | Forkhead box protein P1; Transcriptional repressor. (686 aa) | ||||
TAFA4 | TAFA chemokine like family member 4. (173 aa) | ||||
POU4F3 | POU domain protein. (326 aa) | ||||
COL3A1 | Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. (1460 aa) | ||||
HSPG2 | Heparan sulfate proteoglycan 2. (3948 aa) | ||||
SLC25A14 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (484 aa) | ||||
LGALS3 | Galectin. (258 aa) | ||||
POU4F3-2 | Brain-specific homeobox/POU domain protein 3; May play a role in specifying terminally differentiated neuronal phenotypes; Belongs to the POU transcription factor family. Class-4 subfamily. (341 aa) | ||||
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa) | ||||
SLC25A26 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (328 aa) | ||||
P4HB | Protein disulfide-isomerase; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). Also acts a structural subunit o [...] (547 aa) | ||||
MITF | BHLH domain-containing protein. (519 aa) | ||||
TAFA1 | TAFA chemokine like family member 1. (145 aa) | ||||
TMLHE | Trimethyllysine dioxygenase, mitochondrial; Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML). (418 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (429 aa) | ||||
EDNRB2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (479 aa) | ||||
IRF1 | Interferon regulatory factor 1; Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor (By similarity); Belongs to the IRF family. (414 aa) | ||||
USF1 | BHLH domain-containing protein. (614 aa) | ||||
SLC45A2 | Uncharacterized protein. (543 aa) | ||||
USP3 | Ubiquitin carboxyl-terminal hydrolase. (520 aa) | ||||
BMP15 | TGF_BETA_2 domain-containing protein. (350 aa) | ||||
ACOX2 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (675 aa) | ||||
FAM107A | Family with sequence similarity 107 member A. (175 aa) | ||||
SYP | MARVEL domain-containing protein. (338 aa) |