(6 nodes) (2022) OsRAD51 Plays a Vital Role in Promoting Homologous Recombination in Rice Meiosis. network (Gallus gallus)

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Your Input:
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	RAD50	Zinc-hook domain-containing protein. (1313 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (382 aa)
	BRCA2	Tower domain-containing protein. (3397 aa)
	SMC5	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...] (1065 aa)
	EXO1	Uncharacterized protein. (800 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	BRCA2	ENSGALP00000060844	ENSGALP00000027524	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Tower domain-containing protein.	0.407
BRCA2	ACTB	ENSGALP00000027524	ENSGALP00000060844	Tower domain-containing protein.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.407
BRCA2	EXO1	ENSGALP00000027524	ENSGALP00000017465	Tower domain-containing protein.	Uncharacterized protein.	0.967
BRCA2	RAD50	ENSGALP00000027524	ENSGALP00000039135	Tower domain-containing protein.	Zinc-hook domain-containing protein.	0.608
BRCA2	SMC5	ENSGALP00000027524	ENSGALP00000024348	Tower domain-containing protein.	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	0.457
BRCA2	SPO11	ENSGALP00000027524	ENSGALP00000048999	Tower domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.659
EXO1	BRCA2	ENSGALP00000017465	ENSGALP00000027524	Uncharacterized protein.	Tower domain-containing protein.	0.967
EXO1	RAD50	ENSGALP00000017465	ENSGALP00000039135	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.884
EXO1	SMC5	ENSGALP00000017465	ENSGALP00000024348	Uncharacterized protein.	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	0.806
EXO1	SPO11	ENSGALP00000017465	ENSGALP00000048999	Uncharacterized protein.	SPO11 initiator of meiotic double stranded breaks.	0.895
RAD50	BRCA2	ENSGALP00000039135	ENSGALP00000027524	Zinc-hook domain-containing protein.	Tower domain-containing protein.	0.608
RAD50	EXO1	ENSGALP00000039135	ENSGALP00000017465	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.884
RAD50	SMC5	ENSGALP00000039135	ENSGALP00000024348	Zinc-hook domain-containing protein.	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	0.574
RAD50	SPO11	ENSGALP00000039135	ENSGALP00000048999	Zinc-hook domain-containing protein.	SPO11 initiator of meiotic double stranded breaks.	0.612
SMC5	BRCA2	ENSGALP00000024348	ENSGALP00000027524	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	Tower domain-containing protein.	0.457
SMC5	EXO1	ENSGALP00000024348	ENSGALP00000017465	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	Uncharacterized protein.	0.806
SMC5	RAD50	ENSGALP00000024348	ENSGALP00000039135	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	Zinc-hook domain-containing protein.	0.574
SMC5	SPO11	ENSGALP00000024348	ENSGALP00000048999	Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...]	SPO11 initiator of meiotic double stranded breaks.	0.720
SPO11	BRCA2	ENSGALP00000048999	ENSGALP00000027524	SPO11 initiator of meiotic double stranded breaks.	Tower domain-containing protein.	0.659
SPO11	EXO1	ENSGALP00000048999	ENSGALP00000017465	SPO11 initiator of meiotic double stranded breaks.	Uncharacterized protein.	0.895