(5 nodes) (2022) Association analysis and expression level of ACE polymorphisms with egg-laying trait in Taihang chicken. network (Gallus gallus)

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Your Input:
	REN	Renin; Belongs to the peptidase A1 family. (423 aa)
	ACE2	Angiotensin-converting enzyme. (808 aa)
	OVAL	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white. (386 aa)
	ACE	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. (1281 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE	ACE2	ENSGALP00000039731	ENSGALP00000026662	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	Angiotensin-converting enzyme.	0.605
ACE	GAPDH	ENSGALP00000039731	ENSGALP00000063325	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...]	0.404
ACE	OVAL	ENSGALP00000039731	ENSGALP00000036403	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	0.504
ACE	REN	ENSGALP00000039731	ENSGALP00000000756	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	Renin; Belongs to the peptidase A1 family.	0.981
ACE2	ACE	ENSGALP00000026662	ENSGALP00000039731	Angiotensin-converting enzyme.	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	0.605
ACE2	OVAL	ENSGALP00000026662	ENSGALP00000036403	Angiotensin-converting enzyme.	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	0.436
ACE2	REN	ENSGALP00000026662	ENSGALP00000000756	Angiotensin-converting enzyme.	Renin; Belongs to the peptidase A1 family.	0.981
GAPDH	ACE	ENSGALP00000063325	ENSGALP00000039731	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...]	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	0.404
GAPDH	OVAL	ENSGALP00000063325	ENSGALP00000036403	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...]	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	0.712
OVAL	ACE	ENSGALP00000036403	ENSGALP00000039731	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	0.504
OVAL	ACE2	ENSGALP00000036403	ENSGALP00000026662	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	Angiotensin-converting enzyme.	0.436
OVAL	GAPDH	ENSGALP00000036403	ENSGALP00000063325	Ovalbumin; Non-inhibitory serpin. Storage protein of egg white.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...]	0.712
REN	ACE	ENSGALP00000000756	ENSGALP00000039731	Renin; Belongs to the peptidase A1 family.	Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family.	0.981
REN	ACE2	ENSGALP00000000756	ENSGALP00000026662	Renin; Belongs to the peptidase A1 family.	Angiotensin-converting enzyme.	0.981