node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE | ACE2 | ENSGALP00000039731 | ENSGALP00000026662 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Angiotensin-converting enzyme. | 0.605 |
ACE | AGT | ENSGALP00000039731 | ENSGALP00000018089 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Angiotensinogen; Belongs to the serpin family. | 0.985 |
ACE | GCG | ENSGALP00000039731 | ENSGALP00000032494 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | 0.552 |
ACE | REN | ENSGALP00000039731 | ENSGALP00000000756 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Renin; Belongs to the peptidase A1 family. | 0.981 |
ACE2 | ACE | ENSGALP00000026662 | ENSGALP00000039731 | Angiotensin-converting enzyme. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.605 |
ACE2 | AGT | ENSGALP00000026662 | ENSGALP00000018089 | Angiotensin-converting enzyme. | Angiotensinogen; Belongs to the serpin family. | 0.969 |
ACE2 | REN | ENSGALP00000026662 | ENSGALP00000000756 | Angiotensin-converting enzyme. | Renin; Belongs to the peptidase A1 family. | 0.981 |
AGT | ACE | ENSGALP00000018089 | ENSGALP00000039731 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.985 |
AGT | ACE2 | ENSGALP00000018089 | ENSGALP00000026662 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme. | 0.969 |
AGT | GCG | ENSGALP00000018089 | ENSGALP00000032494 | Angiotensinogen; Belongs to the serpin family. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | 0.526 |
AGT | REN | ENSGALP00000018089 | ENSGALP00000000756 | Angiotensinogen; Belongs to the serpin family. | Renin; Belongs to the peptidase A1 family. | 0.975 |
GCG | ACE | ENSGALP00000032494 | ENSGALP00000039731 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.552 |
GCG | AGT | ENSGALP00000032494 | ENSGALP00000018089 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | Angiotensinogen; Belongs to the serpin family. | 0.526 |
GCG | REN | ENSGALP00000032494 | ENSGALP00000000756 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | Renin; Belongs to the peptidase A1 family. | 0.437 |
REN | ACE | ENSGALP00000000756 | ENSGALP00000039731 | Renin; Belongs to the peptidase A1 family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.981 |
REN | ACE2 | ENSGALP00000000756 | ENSGALP00000026662 | Renin; Belongs to the peptidase A1 family. | Angiotensin-converting enzyme. | 0.981 |
REN | AGT | ENSGALP00000000756 | ENSGALP00000018089 | Renin; Belongs to the peptidase A1 family. | Angiotensinogen; Belongs to the serpin family. | 0.975 |
REN | GCG | ENSGALP00000000756 | ENSGALP00000032494 | Renin; Belongs to the peptidase A1 family. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | 0.437 |