node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APOA1 | APOB | ENSGALP00000011510 | ENSGALP00000026550 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons, VLDL and LDL. It functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.999 |
APOA1 | INS | ENSGALP00000011510 | ENSGALP00000010567 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.594 |
APOB | APOA1 | ENSGALP00000026550 | ENSGALP00000011510 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons, VLDL and LDL. It functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | 0.999 |
APOB | INS | ENSGALP00000026550 | ENSGALP00000010567 | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons, VLDL and LDL. It functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.780 |
B2M | HMBS | ENSGALP00000039454 | ENSGALP00000045666 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | Hydroxymethylbilane synthase. | 0.675 |
B2M | INS | ENSGALP00000039454 | ENSGALP00000010567 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.412 |
B2M | RPL30 | ENSGALP00000039454 | ENSGALP00000054554 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.443 |
HMBS | B2M | ENSGALP00000045666 | ENSGALP00000039454 | Hydroxymethylbilane synthase. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.675 |
INS | APOA1 | ENSGALP00000010567 | ENSGALP00000011510 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. | 0.594 |
INS | APOB | ENSGALP00000010567 | ENSGALP00000026550 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Apolipoprotein B; Apolipoprotein B is a major protein constituent of chylomicrons, VLDL and LDL. It functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.780 |
INS | B2M | ENSGALP00000010567 | ENSGALP00000039454 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.412 |
RPL30 | B2M | ENSGALP00000054554 | ENSGALP00000039454 | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.443 |
RPL30 | RPS16 | ENSGALP00000054554 | ENSGALP00000061899 | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. | 0.999 |
RPL30 | TGM2-2 | ENSGALP00000054554 | ENSGALP00000048054 | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.424 |
RPS16 | RPL30 | ENSGALP00000061899 | ENSGALP00000054554 | Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.999 |
RPS16 | TGM2-2 | ENSGALP00000061899 | ENSGALP00000048054 | Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.970 |
TGM2-2 | RPL30 | ENSGALP00000048054 | ENSGALP00000054554 | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.424 |
TGM2-2 | RPS16 | ENSGALP00000048054 | ENSGALP00000061899 | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. | 0.970 |