STRINGSTRING
TF TF FADD FADD CASP8 CASP8 CASP10 CASP10 CASP18 CASP18 CASP3 CASP3 CASP1 CASP1 TRADD TRADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFOvotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. There are two forms of hen transferrin, ovotransferrin, found in the ovoducts and, serum transferrin, secreted by the liver. Serum transferrin may also have a role in stimulating cell proliferation and is regulated by iron levels. Ovotransferrin has a bacteriostatic function and, is not controlled by iron levels. (756 aa)
FADDFas associated via death domain. (195 aa)
CASP8Uncharacterized protein; Belongs to the peptidase C14A family. (482 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (455 aa)
CASP18Initiator caspase; Belongs to the peptidase C14A family. (464 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (283 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (540 aa)
TRADDTNFRSF1A associated via death domain. (461 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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