(17 nodes) Double-stranded RNA binding motif network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DGCR8	DGCR8 microprocessor complex subunit. (775 aa)
	ADARB1	Uncharacterized protein. (563 aa)
	ADARB2	Adenosine deaminase RNA specific B2 (inactive). (747 aa)
	NKRF	Uncharacterized protein. (774 aa)
	ADAD1	Uncharacterized protein. (361 aa)
	ENSGALP00000068834	DRBM domain-containing protein. (95 aa)
	SON	Uncharacterized protein. (2900 aa)
	ILF3	Uncharacterized protein. (1076 aa)
	ADAR	RNA-specific Adenosine deaminase Transcript variant M. (1153 aa)
	DUS2	Dihydrouridine synthase 2. (490 aa)
	STAU1	Uncharacterized protein. (712 aa)
	EIF2AK2	Uncharacterized protein. (550 aa)
	DICER1	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] (1921 aa)
	DROSHA	Uncharacterized protein. (1336 aa)
	TARBP2	Uncharacterized protein. (263 aa)
	STAU2	Uncharacterized protein. (642 aa)
	STRBP	Spermatid perinuclear RNA-binding protein; May be involved in normal spermatogenesis and sperm function. Binds to double-stranded DNA and RNA (By similarity). (678 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAR	DICER1	ENSGALP00000067956	ENSGALP00000036777	RNA-specific Adenosine deaminase Transcript variant M.	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	0.830
ADAR	DROSHA	ENSGALP00000067956	ENSGALP00000042067	RNA-specific Adenosine deaminase Transcript variant M.	Uncharacterized protein.	0.639
ADAR	EIF2AK2	ENSGALP00000067956	ENSGALP00000017163	RNA-specific Adenosine deaminase Transcript variant M.	Uncharacterized protein.	0.706
ADAR	ILF3	ENSGALP00000067956	ENSGALP00000066818	RNA-specific Adenosine deaminase Transcript variant M.	Uncharacterized protein.	0.430
ADARB2	DROSHA	ENSGALP00000056685	ENSGALP00000042067	Adenosine deaminase RNA specific B2 (inactive).	Uncharacterized protein.	0.440
DGCR8	DICER1	ENSGALP00000054935	ENSGALP00000036777	DGCR8 microprocessor complex subunit.	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	0.997
DGCR8	DROSHA	ENSGALP00000054935	ENSGALP00000042067	DGCR8 microprocessor complex subunit.	Uncharacterized protein.	0.999
DGCR8	ENSGALP00000068834	ENSGALP00000054935	ENSGALP00000068834	DGCR8 microprocessor complex subunit.	DRBM domain-containing protein.	0.730
DGCR8	TARBP2	ENSGALP00000054935	ENSGALP00000048385	DGCR8 microprocessor complex subunit.	Uncharacterized protein.	0.793
DICER1	ADAR	ENSGALP00000036777	ENSGALP00000067956	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	RNA-specific Adenosine deaminase Transcript variant M.	0.830
DICER1	DGCR8	ENSGALP00000036777	ENSGALP00000054935	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	DGCR8 microprocessor complex subunit.	0.997
DICER1	DROSHA	ENSGALP00000036777	ENSGALP00000042067	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	Uncharacterized protein.	0.801
DICER1	EIF2AK2	ENSGALP00000036777	ENSGALP00000017163	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	Uncharacterized protein.	0.713
DICER1	ENSGALP00000068834	ENSGALP00000036777	ENSGALP00000068834	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	DRBM domain-containing protein.	0.965
DICER1	STAU1	ENSGALP00000036777	ENSGALP00000007529	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	Uncharacterized protein.	0.774
DICER1	STAU2	ENSGALP00000036777	ENSGALP00000049789	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	Uncharacterized protein.	0.773
DICER1	TARBP2	ENSGALP00000036777	ENSGALP00000048385	Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...]	Uncharacterized protein.	0.990
DROSHA	ADAR	ENSGALP00000042067	ENSGALP00000067956	Uncharacterized protein.	RNA-specific Adenosine deaminase Transcript variant M.	0.639
DROSHA	ADARB2	ENSGALP00000042067	ENSGALP00000056685	Uncharacterized protein.	Adenosine deaminase RNA specific B2 (inactive).	0.440
DROSHA	DGCR8	ENSGALP00000042067	ENSGALP00000054935	Uncharacterized protein.	DGCR8 microprocessor complex subunit.	0.999