node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE | AGT | ENSGALP00000039731 | ENSGALP00000018089 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Angiotensinogen; Belongs to the serpin family. | 0.985 |
ACE | AGTR1 | ENSGALP00000039731 | ENSGALP00000057556 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.939 |
ACE | AGTR2 | ENSGALP00000039731 | ENSGALP00000067208 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.764 |
AGT | ACE | ENSGALP00000018089 | ENSGALP00000039731 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.985 |
AGT | AGTR1 | ENSGALP00000018089 | ENSGALP00000057556 | Angiotensinogen; Belongs to the serpin family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.999 |
AGT | AGTR2 | ENSGALP00000018089 | ENSGALP00000067208 | Angiotensinogen; Belongs to the serpin family. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.996 |
AGT | BDKRB2 | ENSGALP00000018089 | ENSGALP00000018030 | Angiotensinogen; Belongs to the serpin family. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.506 |
AGT | KNG1 | ENSGALP00000018089 | ENSGALP00000060409 | Angiotensinogen; Belongs to the serpin family. | Kininogen 1. | 0.624 |
AGTR1 | ACE | ENSGALP00000057556 | ENSGALP00000039731 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.939 |
AGTR1 | AGT | ENSGALP00000057556 | ENSGALP00000018089 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Angiotensinogen; Belongs to the serpin family. | 0.999 |
AGTR1 | AGTR2 | ENSGALP00000057556 | ENSGALP00000067208 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.946 |
AGTR1 | BDKRB2 | ENSGALP00000057556 | ENSGALP00000018030 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.400 |
AGTR1 | KNG1 | ENSGALP00000057556 | ENSGALP00000060409 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Kininogen 1. | 0.651 |
AGTR2 | ACE | ENSGALP00000067208 | ENSGALP00000039731 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.764 |
AGTR2 | AGT | ENSGALP00000067208 | ENSGALP00000018089 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Angiotensinogen; Belongs to the serpin family. | 0.996 |
AGTR2 | AGTR1 | ENSGALP00000067208 | ENSGALP00000057556 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.946 |
AGTR2 | BDKRB2 | ENSGALP00000067208 | ENSGALP00000018030 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.499 |
AGTR2 | KNG1 | ENSGALP00000067208 | ENSGALP00000060409 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Kininogen 1. | 0.594 |
BDKRB2 | AGT | ENSGALP00000018030 | ENSGALP00000018089 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | Angiotensinogen; Belongs to the serpin family. | 0.506 |
BDKRB2 | AGTR1 | ENSGALP00000018030 | ENSGALP00000057556 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.400 |