(22 nodes) p53-Independent DNA Damage Response network (Guillardia theta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	L1JUV1_GUITC	Proteasome subunit alpha type. (255 aa)
	L1J7J7_GUITC	Protein kinase domain-containing protein. (138 aa)
	L1JK36_GUITC	Proteasome subunit alpha type. (252 aa)
	L1JNC1_GUITC	Proteasome activator complex subunit. (249 aa)
	L1JT31_GUITC	26S proteasome regulatory complex, subunit RPN2; Belongs to the proteasome subunit S1 family. (991 aa)
	L1JTS7_GUITC	Uncharacterized protein. (2090 aa)
	L1JUN1_GUITC	Protein kinase domain-containing protein. (774 aa)
	L1JWJ0_GUITC	Protein kinase domain-containing protein. (177 aa)
	L1JXL5_GUITC	Uncharacterized protein. (1770 aa)
	L1JI85_GUITC	DUF3437 domain-containing protein. (208 aa)
	L1JI04_GUITC	26S proteasome regulatory complex, subunit PSMD5. (485 aa)
	L1JDG7_GUITC	Protein kinase domain-containing protein. (334 aa)
	L1JA52_GUITC	High mobility group box fusion protein. (188 aa)
	L1I6V7_GUITC	PI31_Prot_N domain-containing protein. (298 aa)
	L1I9X2_GUITC	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (347 aa)
	L1IEB0_GUITC	Protein kinase domain-containing protein. (150 aa)
	L1INU9_GUITC	Ubiquitin-superoxide dismutase fusion protein. (209 aa)
	L1IPI8_GUITC	High mobility group box fusion protein. (187 aa)
	L1IQJ3_GUITC	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (290 aa)
	L1IRB4_GUITC	Ubiquitin_small subunit ribosomal protein S27Ae fusion protein. (181 aa)
	L1IT96_GUITC	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (221 aa)
	L1J4E9_GUITC	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (271 aa)

Your Current Organism:

Guillardia theta

NCBI taxonomy Id: 905079
Other names: G. theta CCMP2712, Guillardia theta CCMP2712

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L1I6V7_GUITC	L1I9X2_GUITC	L1I6V7	L1I9X2	PI31_Prot_N domain-containing protein.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.765
L1I6V7_GUITC	L1INU9_GUITC	L1I6V7	L1INU9	PI31_Prot_N domain-containing protein.	Ubiquitin-superoxide dismutase fusion protein.	0.591
L1I6V7_GUITC	L1IPI8_GUITC	L1I6V7	L1IPI8	PI31_Prot_N domain-containing protein.	High mobility group box fusion protein.	0.591
L1I6V7_GUITC	L1IQJ3_GUITC	L1I6V7	L1IQJ3	PI31_Prot_N domain-containing protein.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.614
L1I6V7_GUITC	L1IRB4_GUITC	L1I6V7	L1IRB4	PI31_Prot_N domain-containing protein.	Ubiquitin_small subunit ribosomal protein S27Ae fusion protein.	0.591
L1I6V7_GUITC	L1IT96_GUITC	L1I6V7	L1IT96	PI31_Prot_N domain-containing protein.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.783
L1I6V7_GUITC	L1J4E9_GUITC	L1I6V7	L1J4E9	PI31_Prot_N domain-containing protein.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.872
L1I6V7_GUITC	L1JA52_GUITC	L1I6V7	L1JA52	PI31_Prot_N domain-containing protein.	High mobility group box fusion protein.	0.591
L1I6V7_GUITC	L1JI04_GUITC	L1I6V7	L1JI04	PI31_Prot_N domain-containing protein.	26S proteasome regulatory complex, subunit PSMD5.	0.735
L1I6V7_GUITC	L1JK36_GUITC	L1I6V7	L1JK36	PI31_Prot_N domain-containing protein.	Proteasome subunit alpha type.	0.765
L1I6V7_GUITC	L1JNC1_GUITC	L1I6V7	L1JNC1	PI31_Prot_N domain-containing protein.	Proteasome activator complex subunit.	0.602
L1I6V7_GUITC	L1JT31_GUITC	L1I6V7	L1JT31	PI31_Prot_N domain-containing protein.	26S proteasome regulatory complex, subunit RPN2; Belongs to the proteasome subunit S1 family.	0.654
L1I6V7_GUITC	L1JUV1_GUITC	L1I6V7	L1JUV1	PI31_Prot_N domain-containing protein.	Proteasome subunit alpha type.	0.897
L1I9X2_GUITC	L1I6V7_GUITC	L1I9X2	L1I6V7	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	PI31_Prot_N domain-containing protein.	0.765
L1I9X2_GUITC	L1INU9_GUITC	L1I9X2	L1INU9	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	Ubiquitin-superoxide dismutase fusion protein.	0.728
L1I9X2_GUITC	L1IPI8_GUITC	L1I9X2	L1IPI8	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	High mobility group box fusion protein.	0.728
L1I9X2_GUITC	L1IQJ3_GUITC	L1I9X2	L1IQJ3	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.994
L1I9X2_GUITC	L1IRB4_GUITC	L1I9X2	L1IRB4	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	Ubiquitin_small subunit ribosomal protein S27Ae fusion protein.	0.728
L1I9X2_GUITC	L1IT96_GUITC	L1I9X2	L1IT96	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.997
L1I9X2_GUITC	L1J4E9_GUITC	L1I9X2	L1J4E9	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family.	0.995