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rapA rapA GEAM_0249 GEAM_0249 dinG dinG GEAM_1796 GEAM_1796 topA topA GEAM_2350 GEAM_2350 sbcD sbcD sbcC sbcC xni xni polA polA recQ recQ
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
rapARapA family RNA polymerase-associated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (965 aa)
GEAM_0249DNA polymerase II; Protein involved in DNA-directed DNA polymerase activity, nucleotide binding, DNA binding, nucleic acid binding, DNA replication and nucleobase-containing compound metabolic process. (766 aa)
dinGATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. (723 aa)
GEAM_1796DinG family ATP-dependent helicase; Protein involved in hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, ATP-dependent helicase activity, nucleic acid binding, ATP binding, DNA binding, hydrolase activity, ATP-dependent DNA helicase activity and nucleobase-containing compound metabolic process. (637 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (865 aa)
GEAM_2350Superfamily II DNA/RNA helicase; Protein involved in ATP binding, DNA binding, hydrolase activity, helicase activity, nucleic acid binding, structural constituent of ribosome and translation. (587 aa)
sbcDSbcD family exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (412 aa)
sbcCSbcC family exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily. (1082 aa)
xniDNA polymerase I; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. (251 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (934 aa)
recQATP-dependent DNA helicase; Protein involved in nucleic acid binding, ATP binding, helicase activity, ATP-dependent helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent DNA helicase activity, nucleotide binding, catalytic activity, DNA recombination, DNA repair, DNA replication, SOS response and cellular metabolic process. (610 aa)
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana ATCC 33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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