STRINGSTRING
EDX86820.1 EDX86820.1 ruvA ruvA ftsH-4 ftsH-4 EDX87019.1 EDX87019.1 EDX87072.1 EDX87072.1 EDX87082.1 EDX87082.1 EDX87206.1 EDX87206.1 EDX87245.1 EDX87245.1 EDX87423.1 EDX87423.1 ychF ychF EDX86763.1 EDX86763.1 S7335_446 S7335_446 S7335_445 S7335_445 ruvB ruvB EDX86511.1 EDX86511.1 recG recG EDX86083.1 EDX86083.1 EDX86049.1 EDX86049.1 clpB-2 clpB-2 EDX85915.1 EDX85915.1 EDX85739.1 EDX85739.1 EDX85708.1 EDX85708.1 S7335_340 S7335_340 EDX85646.1 EDX85646.1 EDX85580.1 EDX85580.1 EDX85526.1 EDX85526.1 uvrA uvrA EDX85395.1 EDX85395.1 ftsH-3 ftsH-3 EDX85224.1 EDX85224.1 EDX85223.1 EDX85223.1 EDX85190.1 EDX85190.1 mutL mutL EDX85005.1 EDX85005.1 S7335_260 S7335_260 EDX84878.1 EDX84878.1 EDX84770.1 EDX84770.1 EDX83701.1 EDX83701.1 ftsH ftsH uvrB uvrB ftsH-2 ftsH-2 EDX83946.1 EDX83946.1 EDX84031.1 EDX84031.1 S7335_176 S7335_176 clpB clpB EDX84367.1 EDX84367.1 clpX clpX EDX84478.1 EDX84478.1 EDX84480.1 EDX84480.1 EDX84531.1 EDX84531.1 EDX84580.1 EDX84580.1 EDX84618.1 EDX84618.1 smc smc mutS2 mutS2 EDX87763.1 EDX87763.1 EDX87780.1 EDX87780.1 deaD deaD EDX87859.1 EDX87859.1 S7335_634 S7335_634 S7335_636 S7335_636 S7335_682 S7335_682 ftsH-5 ftsH-5 S7335_800 S7335_800 S7335_987 S7335_987 S7335_999 S7335_999
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDX86820.1UvrD/REP helicase subfamily; [L] COG0210 Superfamily I DNA and RNA helicases. (786 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (207 aa)
ftsH-4ATP-dependent metallopeptidase HflB subfamily; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (630 aa)
EDX87019.1Cadmium-translocating P-type ATPase; [P] COG2217 Cation transport ATPase. (781 aa)
EDX87072.1Hypothetical protein; [L] COG0210 Superfamily I DNA and RNA helicases. (115 aa)
EDX87082.1ATPase, P-type, HAD superfamily, subfamily IC, putative; [P] COG0474 Cation transport ATPase. (920 aa)
EDX87206.1ATPase, AAA family protein; [O] COG0464 ATPases of the AAA+ class. (508 aa)
EDX87245.1ATPase, P-type, HAD superfamily, subfamily IC, putative; [P] COG0474 Cation transport ATPase. (949 aa)
EDX87423.1Conserved domain protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (365 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
EDX86763.1[S] COG4633 Uncharacterized protein conserved in bacteria. (86 aa)
S7335_446UvrD/REP helicase domain protein; [L] COG0210 Superfamily I DNA and RNA helicases. (700 aa)
S7335_445Cadmium-translocating P-type ATPase; [P] COG2217 Cation transport ATPase. (647 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (399 aa)
EDX86511.1ATPase, AAA family protein; [O] COG0464 ATPases of the AAA+ class. (508 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (872 aa)
EDX86083.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (453 aa)
EDX86049.1Copper-translocating P-type ATPase; [P] COG2217 Cation transport ATPase. (761 aa)
clpB-2ATPase, AAA family; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. (941 aa)
EDX85915.1Hypothetical protein; [P] COG0003 Oxyanion-translocating ATPase. (381 aa)
EDX85739.1Copper-translocating P-type ATPase; [P] COG2217 Cation transport ATPase. (756 aa)
EDX85708.1Hypothetical protein. (220 aa)
S7335_340Hypothetical protein; [P] COG2217 Cation transport ATPase. (40 aa)
EDX85646.1Copper-translocating P-type ATPase; [P] COG2217 Cation transport ATPase. (841 aa)
EDX85580.1[L] COG0210 Superfamily I DNA and RNA helicases. (784 aa)
EDX85526.1Conserved domain protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (356 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1032 aa)
EDX85395.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (460 aa)
ftsH-3ATP-dependent metallopeptidase HflB subfamily; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (626 aa)
EDX85224.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (222 aa)
EDX85223.1[C] COG4451 Ribulose bisphosphate carboxylase small subunit. (455 aa)
EDX85190.1Hypothetical protein; [P] COG2217 Cation transport ATPase. (164 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (570 aa)
EDX85005.1ATPase, AAA family; [O] COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (826 aa)
S7335_260ATPase, P-type, HAD superfamily, subfamily IC, putative; [P] COG0474 Cation transport ATPase. (970 aa)
EDX84878.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit; M protein repeat. (573 aa)
EDX84770.1Tetratricopeptide repeat domain protein; [M] COG0381 UDP-N-acetylglucosamine 2-epimerase. (987 aa)
EDX83701.1Hypothetical protein; [O] COG0464 ATPases of the AAA+ class. (482 aa)
ftsHATP-dependent metallopeptidase HflB subfamily; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (668 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (680 aa)
ftsH-2ATP-dependent metallopeptidase HflB subfamily; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (613 aa)
EDX83946.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (721 aa)
EDX84031.1Cadmium-translocating P-type ATPase; [P] COG2217 Cation transport ATPase. (655 aa)
S7335_176ATPase, AAA family protein; [O] COG0464 ATPases of the AAA+ class. (315 aa)
clpBATPase, AAA family; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (871 aa)
EDX84367.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (674 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (443 aa)
EDX84478.1Arsenite-activated ATPase (arsA) subfamily; [P] COG0003 Oxyanion-translocating ATPase. (388 aa)
EDX84480.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (93 aa)
EDX84531.1Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (493 aa)
EDX84580.1Septum site-determining protein MinD; [D] COG2894 Septum formation inhibitor-activating ATPase. (265 aa)
EDX84618.1[S] COG4633 Uncharacterized protein conserved in bacteria. (178 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1230 aa)
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (798 aa)
EDX87763.1DEAD/DEAH box helicase domain protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family. (471 aa)
EDX87780.1ATPase, AAA family; [O] COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family. (822 aa)
deaDDbpA RNA binding domain family; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (570 aa)
EDX87859.1ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; Molecular chaperone. Has ATPase activity. (658 aa)
S7335_634ATPase, AAA family protein; [O] COG0464 ATPases of the AAA+ class. (732 aa)
S7335_636Hypothetical protein; [P] COG2217 Cation transport ATPase. (49 aa)
S7335_682ATPase, AAA family protein; [O] COG0464 ATPases of the AAA+ class. (486 aa)
ftsH-5ATP-dependent metallopeptidase HflB subfamily; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (652 aa)
S7335_800ATPase, P-type, HAD superfamily, subfamily IC, putative; [P] COG0474 Cation transport ATPase. (936 aa)
S7335_987Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit. (623 aa)
S7335_999Hypothetical protein. (234 aa)
Your Current Organism:
Synechococcus sp. PCC7335
NCBI taxonomy Id: 91464
Other names: Coccusdissimilis mexicanus PCC 7335, S. sp. PCC 7335, Synechococcus PCC 7335, Synechococcus PCC7335, Synechococcus mexicanus PCC 7335, Synechococcus sp. PCC 7335
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