(25 nodes) SUMOylation of transcription factors network (Parus major)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TP53BP1	Tumor suppressor p53-binding protein 1 isoform X1. (2048 aa)
	PIAS4	E3 SUMO-protein ligase PIAS4 isoform X1. (492 aa)
	VTCN1	V-set domain-containing T-cell activation inhibitor 1. (270 aa)
	PIAS1	E3 SUMO-protein ligase PIAS1 isoform X1. (651 aa)
	ENSPMJP00000013025	annotation not available (71 aa)
	MTA1	Metastasis-associated protein MTA1. (633 aa)
	TFAP2C	Transcription factor AP-2 gamma. (448 aa)
	MITF	Microphthalmia-associated transcription factor isoform X1. (519 aa)
	ZMIZ1	Zinc finger MIZ domain-containing protein 1 isoform X1. (1043 aa)
	SP3	Transcription factor Sp3. (738 aa)
	SP5	Transcription factor Sp5. (367 aa)
	HIC1	Hypermethylated in cancer 1 protein. (665 aa)
	SP4	Transcription factor Sp4. (777 aa)
	PIAS2	E3 SUMO-protein ligase PIAS2 isoform X5. (724 aa)
	UBE2I	Ubiquitin-conjugating enzyme E2 I. (325 aa)
	SUMO2	Small ubiquitin-related modifier 2. (52 aa)
	FOXD2	LOW QUALITY PROTEIN: forkhead box protein D2. (418 aa)
	KCTD2	BTB/POZ domain-containing protein KCTD2/5/17. (236 aa)
	ENSPMJP00000021789	annotation not available (374 aa)
	SUMO1	Small ubiquitin-related modifier 1. (101 aa)
	LOC107208897	Small ubiquitin-related modifier 3-like. (95 aa)
	ZMIZ2	Zinc finger MIZ domain-containing protein 2 isoform X1. (908 aa)
	TFEB	Transcription factor EB. (457 aa)
	HIC2	Hypermethylated in cancer 2 protein. (591 aa)
	FOXD3	Forkhead box D3. (317 aa)

Your Current Organism:

Parus major

NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KCTD2	LOC107208897	ENSPMJP00000000429	ENSPMJP00000022297	BTB/POZ domain-containing protein KCTD2/5/17.	Small ubiquitin-related modifier 3-like.	0.889
KCTD2	MITF	ENSPMJP00000000429	ENSPMJP00000006642	BTB/POZ domain-containing protein KCTD2/5/17.	Microphthalmia-associated transcription factor isoform X1.	0.401
KCTD2	PIAS1	ENSPMJP00000000429	ENSPMJP00000013092	BTB/POZ domain-containing protein KCTD2/5/17.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.790
KCTD2	PIAS2	ENSPMJP00000000429	ENSPMJP00000003795	BTB/POZ domain-containing protein KCTD2/5/17.	E3 SUMO-protein ligase PIAS2 isoform X5.	0.790
KCTD2	PIAS4	ENSPMJP00000000429	ENSPMJP00000015446	BTB/POZ domain-containing protein KCTD2/5/17.	E3 SUMO-protein ligase PIAS4 isoform X1.	0.790
KCTD2	SUMO1	ENSPMJP00000000429	ENSPMJP00000024839	BTB/POZ domain-containing protein KCTD2/5/17.	Small ubiquitin-related modifier 1.	0.957
KCTD2	SUMO2	ENSPMJP00000000429	ENSPMJP00000000475	BTB/POZ domain-containing protein KCTD2/5/17.	Small ubiquitin-related modifier 2.	0.889
KCTD2	TP53BP1	ENSPMJP00000000429	ENSPMJP00000015907	BTB/POZ domain-containing protein KCTD2/5/17.	Tumor suppressor p53-binding protein 1 isoform X1.	0.686
KCTD2	ZMIZ1	ENSPMJP00000000429	ENSPMJP00000004408	BTB/POZ domain-containing protein KCTD2/5/17.	Zinc finger MIZ domain-containing protein 1 isoform X1.	0.744
KCTD2	ZMIZ2	ENSPMJP00000000429	ENSPMJP00000019893	BTB/POZ domain-containing protein KCTD2/5/17.	Zinc finger MIZ domain-containing protein 2 isoform X1.	0.744
LOC107208897	KCTD2	ENSPMJP00000022297	ENSPMJP00000000429	Small ubiquitin-related modifier 3-like.	BTB/POZ domain-containing protein KCTD2/5/17.	0.889
LOC107208897	PIAS1	ENSPMJP00000022297	ENSPMJP00000013092	Small ubiquitin-related modifier 3-like.	E3 SUMO-protein ligase PIAS1 isoform X1.	0.781
LOC107208897	PIAS2	ENSPMJP00000022297	ENSPMJP00000003795	Small ubiquitin-related modifier 3-like.	E3 SUMO-protein ligase PIAS2 isoform X5.	0.781
LOC107208897	PIAS4	ENSPMJP00000022297	ENSPMJP00000015446	Small ubiquitin-related modifier 3-like.	E3 SUMO-protein ligase PIAS4 isoform X1.	0.838
LOC107208897	SUMO1	ENSPMJP00000022297	ENSPMJP00000024839	Small ubiquitin-related modifier 3-like.	Small ubiquitin-related modifier 1.	0.677
LOC107208897	TP53BP1	ENSPMJP00000022297	ENSPMJP00000015907	Small ubiquitin-related modifier 3-like.	Tumor suppressor p53-binding protein 1 isoform X1.	0.714
LOC107208897	UBE2I	ENSPMJP00000022297	ENSPMJP00000000951	Small ubiquitin-related modifier 3-like.	Ubiquitin-conjugating enzyme E2 I.	0.962
LOC107208897	ZMIZ1	ENSPMJP00000022297	ENSPMJP00000004408	Small ubiquitin-related modifier 3-like.	Zinc finger MIZ domain-containing protein 1 isoform X1.	0.689
LOC107208897	ZMIZ2	ENSPMJP00000022297	ENSPMJP00000019893	Small ubiquitin-related modifier 3-like.	Zinc finger MIZ domain-containing protein 2 isoform X1.	0.689
MITF	KCTD2	ENSPMJP00000006642	ENSPMJP00000000429	Microphthalmia-associated transcription factor isoform X1.	BTB/POZ domain-containing protein KCTD2/5/17.	0.401