STRINGSTRING
SET26951.1 SET26951.1 gcvPA gcvPA SET25827.1 SET25827.1 SET25846.1 SET25846.1 SET27167.1 SET27167.1 gcvPA-2 gcvPA-2 SET37099.1 SET37099.1 SET35631.1 SET35631.1 SET31491.1 SET31491.1 SET31544.1 SET31544.1 glyA glyA gpmA-2 gpmA-2 SET57482.1 SET57482.1 SET56212.1 SET56212.1 SET56517.1 SET56517.1 SET46633.1 SET46633.1 gcvPB-2 gcvPB-2 serC serC SET63528.1 SET63528.1 SET61328.1 SET61328.1 thrB thrB gcvPB gcvPB SES84177.1 SES84177.1 SES85342.1 SES85342.1 SET01381.1 SET01381.1 SET07690.1 SET07690.1 SET11188.1 SET11188.1 SET11425.1 SET11425.1 SET11906.1 SET11906.1 SET12410.1 SET12410.1 SET13887.1 SET13887.1 SET14737.1 SET14737.1 ilvA ilvA SET17348.1 SET17348.1 SET71616.1 SET71616.1 SET20636.1 SET20636.1 SET24612.1 SET24612.1 SES72029.1 SES72029.1 asd asd trpB trpB trpA trpA gpmA gpmA gcvT gcvT gcvH gcvH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SET26951.1Pyrroloquinoline-quinone synthase. (248 aa)
gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (450 aa)
SET25827.1Hypothetical protein. (243 aa)
SET25846.1Hypothetical protein. (223 aa)
SET27167.1Dihydrolipoamide dehydrogenase. (487 aa)
gcvPA-2Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (450 aa)
SET37099.1Hypothetical protein. (393 aa)
SET35631.1Glycine/sarcosine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. (272 aa)
SET31491.1L-threonine synthase. (470 aa)
SET31544.1Homoserine dehydrogenase. (438 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa)
gpmA-2Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (249 aa)
SET57482.1Aminopeptidase P Metallo peptidase. MEROPS family M24B. (434 aa)
SET56212.12-amino-3-ketobutyrate coenzyme A ligase. (426 aa)
SET56517.1Probable phosphoglycerate mutase. (174 aa)
SET46633.1Aspartate kinase; Belongs to the aspartokinase family. (409 aa)
gcvPB-2Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (501 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (364 aa)
SET63528.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (402 aa)
SET61328.1Dihydrolipoamide dehydrogenase. (602 aa)
thrBHomoserine kinase; Belongs to the pseudomonas-type ThrB family. (316 aa)
gcvPBGlycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (483 aa)
SES84177.1L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
SES85342.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (259 aa)
SET01381.1Alanine-glyoxylate aminotransferase apoenzyme. (405 aa)
SET07690.1Choline dehydrogenase. (619 aa)
SET11188.1Arsenate reductase. (115 aa)
SET11425.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
SET11906.1Uncharacterized conserved protein, contains ferritin-like DUF455 domain. (266 aa)
SET12410.1Phenylpropionate dioxygenase, large terminal subunit. (368 aa)
SET13887.1Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
SET14737.1Dihydrolipoamide dehydrogenase. (473 aa)
ilvAL-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (503 aa)
SET17348.1Hydroxypyruvate reductase. (425 aa)
SET71616.1Arsenate reductase; Belongs to the ArsC family. (118 aa)
SET20636.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (727 aa)
SET24612.1Zn-dependent protease (includes SpoIVFB); Belongs to the peptidase M50B family. (373 aa)
SES72029.1Phosphoserine phosphatase. (277 aa)
asdAspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (268 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (245 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (363 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
Your Current Organism:
Nitrosomonas marina
NCBI taxonomy Id: 917
Other names: N. marina, Nitrosomonas marina Koops et al. 2001, strain Nm 22
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