STRINGSTRING
gcvH gcvH gcvT gcvT SES71698.1 SES71698.1 SES63103.1 SES63103.1 cbbL cbbL SES66215.1 SES66215.1 SES65181.1 SES65181.1 SET54778.1 SET54778.1 mdh mdh gcvPB-2 gcvPB-2 gcvPA-2 gcvPA-2 SET37610.1 SET37610.1 glyA glyA SET31773.1 SET31773.1 SET27567.1 SET27567.1 SET27167.1 SET27167.1 SET25846.1 SET25846.1 SET25827.1 SET25827.1 SET20636.1 SET20636.1 SET17487.1 SET17487.1 SET17348.1 SET17348.1 SET14737.1 SET14737.1 SET13887.1 SET13887.1 SET14495.1 SET14495.1 SET11906.1 SET11906.1 SET11476.1 SET11476.1 SET11188.1 SET11188.1 SET08825.1 SET08825.1 SET08103.1 SET08103.1 SET01381.1 SET01381.1 SES81723.1 SES81723.1 SES81519.1 SES81519.1 gcvPB gcvPB gcvPA gcvPA SET59487.1 SET59487.1 SET57356.1 SET57356.1 cbbL-2 cbbL-2 sucD-2 sucD-2 sucC-2 sucC-2 SET56455.1 SET56455.1 acsA acsA SET54354.1 SET54354.1 SET54847.1 SET54847.1 SET54819.1 SET54819.1 SET54800.1 SET54800.1 SET50576.1 SET50576.1 SET71616.1 SET71616.1 SET61328.1 SET61328.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (363 aa)
SES71698.1L-glutamine synthetase. (457 aa)
SES63103.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (442 aa)
cbbLRibulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (472 aa)
SES66215.1Ribulose 1,5-bisphosphate carboxylase small subunit. (118 aa)
SES65181.1Formiminoglutamase. (254 aa)
SET54778.1Glycolate oxidase iron-sulfur subunit. (414 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
gcvPB-2Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (501 aa)
gcvPA-2Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (450 aa)
SET37610.1acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (416 aa)
SET31773.1Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (253 aa)
SET27567.1L-glutamine synthetase. (723 aa)
SET27167.1Dihydrolipoamide dehydrogenase. (487 aa)
SET25846.1Hypothetical protein. (223 aa)
SET25827.1Hypothetical protein. (243 aa)
SET20636.1Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (727 aa)
SET17487.1L-glutamine synthetase. (469 aa)
SET17348.1Hydroxypyruvate reductase. (425 aa)
SET14737.1Dihydrolipoamide dehydrogenase. (473 aa)
SET13887.1Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa)
SET14495.1Citrate synthase; Belongs to the citrate synthase family. (432 aa)
SET11906.1Uncharacterized conserved protein, contains ferritin-like DUF455 domain. (266 aa)
SET11476.1Phosphoglycolate phosphatase, HAD superfamily. (214 aa)
SET11188.1Arsenate reductase. (115 aa)
SET08825.1NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit. (592 aa)
SET08103.1Hypothetical protein. (404 aa)
SET01381.1Alanine-glyoxylate aminotransferase apoenzyme. (405 aa)
SES81723.1Aconitase. (951 aa)
SES81519.1Glycolate oxidase iron-sulfur subunit. (464 aa)
gcvPBGlycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (483 aa)
gcvPAGlycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (450 aa)
SET59487.1Catalase; Belongs to the catalase family. (98 aa)
SET57356.1Ribulose 1,5-bisphosphate carboxylase small subunit. (144 aa)
cbbL-2Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (491 aa)
sucD-2Malate thiokinase small subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucC-2malate-CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (393 aa)
SET56455.1beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (315 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (655 aa)
SET54354.1Transcriptional regulator, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (153 aa)
SET54847.12-hydroxy-3-oxopropionate reductase. (304 aa)
SET54819.1Glycolate oxidase. (483 aa)
SET54800.1Glycolate oxidase FAD binding subunit. (358 aa)
SET50576.1L-lactate dehydrogenase complex protein LldE. (263 aa)
SET71616.1Arsenate reductase; Belongs to the ArsC family. (118 aa)
SET61328.1Dihydrolipoamide dehydrogenase. (602 aa)
Your Current Organism:
Nitrosomonas marina
NCBI taxonomy Id: 917
Other names: N. marina, Nitrosomonas marina Koops et al. 2001, strain Nm 22
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