24 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_09310	TFIIS N-terminal domain-containing protein. (395 aa)
	PV08_08398	Uncharacterized protein. (74 aa)
	PV08_03341	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1294 aa)
	PV08_01121	Uncharacterized protein. (1215 aa)
	PV08_09699	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1089 aa)
	PV08_09759	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (117 aa)
	PV08_03001	Uncharacterized protein. (1024 aa)
	PV08_03302	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1772 aa)
	PV08_00612	S1 domain-containing protein. (167 aa)
	PV08_01340	RNA_pol_L_2 domain-containing protein. (243 aa)
	PV08_10374	Plus3 domain-containing protein. (611 aa)
	PV08_10937	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1421 aa)
	PV08_09062	RPOLD domain-containing protein. (334 aa)
	PV08_09898	Uncharacterized protein. (238 aa)
	PV08_07727	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (855 aa)
	PV08_11001	DNA-directed RNA polymerase I, II, and III subunit RPABC5. (86 aa)
	PV08_00095	CDC73_C domain-containing protein. (444 aa)
	PV08_00518	RPOL4c domain-containing protein. (152 aa)
	PV08_00705	Uncharacterized protein. (152 aa)
	PV08_01865	Transcription elongation factor S-II. (305 aa)
	PV08_06965	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (616 aa)
	PV08_05224	Uncharacterized protein. (490 aa)
	PV08_04400	CFEM domain-containing protein. (275 aa)
	PV08_00404	Uncharacterized protein. (540 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00095	PV08_00404	A0A0D2BKS5	A0A0D2C8E2	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_00518	A0A0D2BKS5	A0A0D2BLX8	CDC73_C domain-containing protein.	RPOL4c domain-containing protein.	0.909
PV08_00095	PV08_00612	A0A0D2BKS5	A0A0D2A5L2	CDC73_C domain-containing protein.	S1 domain-containing protein.	0.926
PV08_00095	PV08_00705	A0A0D2BKS5	A0A0D2BNM3	CDC73_C domain-containing protein.	Uncharacterized protein.	0.923
PV08_00095	PV08_01121	A0A0D2BKS5	A0A0D1YZ56	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_01340	A0A0D2BKS5	A0A0D2A7J8	CDC73_C domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.921
PV08_00095	PV08_01865	A0A0D2BKS5	A0A0D2BS72	CDC73_C domain-containing protein.	Transcription elongation factor S-II.	0.943
PV08_00095	PV08_03001	A0A0D2BKS5	A0A0D2A156	CDC73_C domain-containing protein.	Uncharacterized protein.	0.995
PV08_00095	PV08_03302	A0A0D2BKS5	A0A0D2A281	CDC73_C domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.974
PV08_00095	PV08_03341	A0A0D2BKS5	A0A0D1YUW7	CDC73_C domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.943
PV08_00095	PV08_04400	A0A0D2BKS5	A0A0D2C0L8	CDC73_C domain-containing protein.	CFEM domain-containing protein.	0.922
PV08_00095	PV08_05224	A0A0D2BKS5	A0A0D2BV93	CDC73_C domain-containing protein.	Uncharacterized protein.	0.999
PV08_00095	PV08_06965	A0A0D2BKS5	A0A0D2BSF9	CDC73_C domain-containing protein.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.994
PV08_00095	PV08_08398	A0A0D2BKS5	A0A0D1YDS8	CDC73_C domain-containing protein.	Uncharacterized protein.	0.906
PV08_00095	PV08_09062	A0A0D2BKS5	A0A0D2AZ98	CDC73_C domain-containing protein.	RPOLD domain-containing protein.	0.931
PV08_00095	PV08_09310	A0A0D2BKS5	A0A0D1YAV9	CDC73_C domain-containing protein.	TFIIS N-terminal domain-containing protein.	0.723
PV08_00095	PV08_09699	A0A0D2BKS5	A0A0D1ZHN6	CDC73_C domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.978
PV08_00095	PV08_09759	A0A0D2BKS5	A0A0D1ZHW4	CDC73_C domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.951
PV08_00095	PV08_09898	A0A0D2BKS5	A0A0D2B1Z3	CDC73_C domain-containing protein.	Uncharacterized protein.	0.934
PV08_00095	PV08_10374	A0A0D2BKS5	A0A0D2AXD5	CDC73_C domain-containing protein.	Plus3 domain-containing protein.	0.995