STRINGSTRING
PV08_09199 PV08_09199 PV08_09255 PV08_09255 PV08_07546 PV08_07546 PV08_07661 PV08_07661 ADK2 ADK2 PV08_02679 PV08_02679 PV08_03195 PV08_03195 PV08_03686 PV08_03686 PV08_00310 PV08_00310 PV08_10096 PV08_10096 PV08_08359 PV08_08359 PV08_08700 PV08_08700 PV08_06983 PV08_06983 PV08_02490 PV08_02490 PV08_02951 PV08_02951 PV08_00271 PV08_00271 PV08_00817 PV08_00817 PV08_01395 PV08_01395 PV08_11949 PV08_11949 PV08_09484 PV08_09484 PV08_09344 PV08_09344 PV08_08462 PV08_08462 PV08_06836 PV08_06836 PV08_07347 PV08_07347 PV08_07678 PV08_07678 PV08_05195 PV08_05195 PV08_05489 PV08_05489 PV08_06069 PV08_06069 PV08_05795 PV08_05795 PV08_06106 PV08_06106 PV08_03927 PV08_03927 PV08_04103 PV08_04103 PV08_02491 PV08_02491 PV08_03037 PV08_03037 PV08_02758 PV08_02758 PV08_02899 PV08_02899 PV08_02919 PV08_02919 AAH1 AAH1 PV08_09596 PV08_09596 PV08_00888 PV08_00888 ADK1 ADK1 PV08_08416 PV08_08416 PV08_08925 PV08_08925 PV08_02178 PV08_02178 PV08_06970 PV08_06970 PV08_07131 PV08_07131 PV08_07368 PV08_07368 PV08_05525 PV08_05525 PV08_06050 PV08_06050 PV08_06320 PV08_06320 PV08_03887 PV08_03887 PV08_04355 PV08_04355 AAH1-2 AAH1-2 PV08_03633 PV08_03633 PV08_00328 PV08_00328 PV08_00919 PV08_00919 PV08_01069 PV08_01069
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_09199Uncharacterized protein. (205 aa)
PV08_09255Ribonucleoside-diphosphate reductase small chain. (408 aa)
PV08_07546Deoxyuridine 5'-triphosphate nucleotidohydrolase. (192 aa)
PV08_07661CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (568 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
PV08_02679FSH1 domain-containing protein. (271 aa)
PV08_03195A_deaminase domain-containing protein. (614 aa)
PV08_03686Adenosine deaminase. (371 aa)
PV08_00310Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (172 aa)
PV08_10096DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (424 aa)
PV08_08359Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (693 aa)
PV08_08700Metallophos domain-containing protein. (616 aa)
PV08_06983Uncharacterized protein. (301 aa)
PV08_02490Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (465 aa)
PV08_02951GMP synthase [glutamine-hydrolyzing]. (545 aa)
PV08_00271Thymidylate synthase. (387 aa)
PV08_00817Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (407 aa)
PV08_01395IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation. (388 aa)
PV08_11949GRIP domain-containing protein. (585 aa)
PV08_09484Uncharacterized protein. (465 aa)
PV08_09344Uncharacterized protein. (449 aa)
PV08_08462Guanylate kinase. (207 aa)
PV08_06836Nudix hydrolase domain-containing protein. (158 aa)
PV08_07347Adenosine deaminase. (381 aa)
PV08_07678S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (314 aa)
PV08_05195Uncharacterized protein. (354 aa)
PV08_05489Adenine phosphoribosyltransferase. (214 aa)
PV08_06069IU_nuc_hydro domain-containing protein. (365 aa)
PV08_05795Uncharacterized protein. (410 aa)
PV08_06106Uncharacterized protein. (421 aa)
PV08_03927PfkB domain-containing protein. (338 aa)
PV08_04103Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
PV08_02491Thymidylate kinase. (230 aa)
PV08_03037IU_nuc_hydro domain-containing protein. (437 aa)
PV08_027585'/3'-nucleotidase SurE. (812 aa)
PV08_02899Uncharacterized protein. (338 aa)
PV08_02919Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (882 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (363 aa)
PV08_09596Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (241 aa)
PV08_008883-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
PV08_08416Flavoprotein domain-containing protein. (237 aa)
PV08_08925PRK domain-containing protein. (326 aa)
PV08_02178Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (576 aa)
PV08_06970Pyrimidine 5'-nucleotidase. (248 aa)
PV08_07131PfkB domain-containing protein. (367 aa)
PV08_07368CMP/dCMP-type deaminase domain-containing protein. (412 aa)
PV08_05525Uncharacterized protein. (301 aa)
PV08_06050Uncharacterized protein. (798 aa)
PV08_06320PfkB domain-containing protein. (785 aa)
PV08_03887Uncharacterized protein. (246 aa)
PV08_04355Metallophos domain-containing protein. (602 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (350 aa)
PV08_03633Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
PV08_00328HD domain-containing protein. (268 aa)
PV08_00919Uncharacterized protein. (394 aa)
PV08_01069Uncharacterized protein; Belongs to the 5'-nucleotidase family. (638 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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