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PV08_07661 PV08_07661 ADK2 ADK2 PV08_08359 PV08_08359 PV08_06983 PV08_06983 PV08_02951 PV08_02951 PV08_11949 PV08_11949 PV08_08462 PV08_08462 PV08_06836 PV08_06836 PV08_07347 PV08_07347 PV08_03927 PV08_03927 PV08_04103 PV08_04103 PV08_02758 PV08_02758 PV08_09596 PV08_09596 PV08_00888 PV08_00888 ADK1 ADK1 PV08_02178 PV08_02178 PV08_03887 PV08_03887 PV08_03633 PV08_03633
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_07661CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (568 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
PV08_08359Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (693 aa)
PV08_06983Uncharacterized protein. (301 aa)
PV08_02951GMP synthase [glutamine-hydrolyzing]. (545 aa)
PV08_11949GRIP domain-containing protein. (585 aa)
PV08_08462Guanylate kinase. (207 aa)
PV08_06836Nudix hydrolase domain-containing protein. (158 aa)
PV08_07347Adenosine deaminase. (381 aa)
PV08_03927PfkB domain-containing protein. (338 aa)
PV08_04103Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (192 aa)
PV08_027585'/3'-nucleotidase SurE. (812 aa)
PV08_09596Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (241 aa)
PV08_008883-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
PV08_02178Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (576 aa)
PV08_03887Uncharacterized protein. (246 aa)
PV08_03633Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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