25 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_11137	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (505 aa)
	PV08_08028	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (768 aa)
	PV08_05231	Uncharacterized protein. (533 aa)
	PV08_03724	Uncharacterized protein. (871 aa)
	PV08_03991	RECA_2 domain-containing protein. (483 aa)
	PV08_04352	Uncharacterized protein. (379 aa)
	PV08_05176	Uncharacterized protein. (308 aa)
	PV08_11329	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (349 aa)
	PV08_08808	SAE2 domain-containing protein. (581 aa)
	PV08_08818	RECA_2 domain-containing protein. (447 aa)
	PV08_06173	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	PV08_04892	FHA domain-containing protein. (854 aa)
	PV08_01972	Uncharacterized protein. (275 aa)
	PV08_10289	Rad51 domain-containing protein. (519 aa)
	PV08_08117	Uncharacterized protein. (1653 aa)
	PV08_07322	Uncharacterized protein. (1513 aa)
	PV08_07825	Uncharacterized protein. (77 aa)
	PV08_03907	Uncharacterized protein. (1179 aa)
	PV08_10769	Uncharacterized protein. (738 aa)
	PV08_03499	Uncharacterized protein. (1306 aa)
	PV08_00388	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (457 aa)
	PV08_01684	AAA domain-containing protein. (1093 aa)
	PV08_04405	Checkpoint protein; Belongs to the HUS1 family. (348 aa)
	PV08_00894	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2287 aa)
	PV08_02129	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2916 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00388	PV08_00894	A0A0D2BLI8	A0A0D2C9R0	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.918
PV08_00388	PV08_01684	A0A0D2BLI8	A0A0D2BRS7	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	AAA domain-containing protein.	0.743
PV08_00388	PV08_01972	A0A0D2BLI8	A0A0D2A9E5	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.772
PV08_00388	PV08_02129	A0A0D2BLI8	A0A0D2CDF7	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.950
PV08_00388	PV08_03499	A0A0D2BLI8	A0A0D2BKS6	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.659
PV08_00388	PV08_03724	A0A0D2BLI8	A0A0D1YNA6	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.757
PV08_00388	PV08_03907	A0A0D2BLI8	A0A0D2BCL3	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.698
PV08_00388	PV08_03991	A0A0D2BLI8	A0A0D1YNU8	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	RECA_2 domain-containing protein.	0.693
PV08_00388	PV08_04352	A0A0D2BLI8	A0A0D1YPM7	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.687
PV08_00388	PV08_04405	A0A0D2BLI8	A0A0D2C0M0	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Checkpoint protein; Belongs to the HUS1 family.	0.999
PV08_00388	PV08_04892	A0A0D2BLI8	A0A0D1ZYG5	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	FHA domain-containing protein.	0.776
PV08_00388	PV08_05176	A0A0D2BLI8	A0A0D1YRX9	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.757
PV08_00388	PV08_05231	A0A0D2BLI8	A0A0D1YJM9	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.852
PV08_00388	PV08_06173	A0A0D2BLI8	A0A0D1ZTL9	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.954
PV08_00388	PV08_07322	A0A0D2BLI8	A0A0D2B6P6	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.757
PV08_00388	PV08_07825	A0A0D2BLI8	A0A0D2B841	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.972
PV08_00388	PV08_08028	A0A0D2BLI8	A0A0D1YD01	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.771
PV08_00388	PV08_08117	A0A0D2BLI8	A0A0D2B2U5	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.862
PV08_00388	PV08_08808	A0A0D2BLI8	A0A0D1ZLC5	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	SAE2 domain-containing protein.	0.733
PV08_00388	PV08_08818	A0A0D2BLI8	A0A0D1ZLD2	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	RECA_2 domain-containing protein.	0.652