(87 nodes) Fatty acid beta-oxidation, and Oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor network (Exophiala spinifera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_11003	Uncharacterized protein. (548 aa)
	PV08_09406	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
	PV08_09421	ACB domain-containing protein. (102 aa)
	PV08_09608	Uncharacterized protein. (422 aa)
	PV08_08353	Uncharacterized protein. (350 aa)
	PV08_06982	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
	PV08_07083	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (416 aa)
	PV08_05821	Uncharacterized protein. (427 aa)
	PV08_06357	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (703 aa)
	PV08_03769	Uncharacterized protein. (727 aa)
	PV08_04167	Uncharacterized protein. (903 aa)
	PV08_04412	Uncharacterized protein. (432 aa)
	PV08_03418	Uncharacterized protein. (292 aa)
	PV08_03423	SCP2 domain-containing protein. (126 aa)
	PV08_00053	Peroxisomal hydratase-dehydrogenase-epimerase. (901 aa)
	PV08_00676	TPR_REGION domain-containing protein. (644 aa)
	PV08_01041	ETF domain-containing protein. (256 aa)
	PV08_01273	Uncharacterized protein. (460 aa)
	PV08_01319	Cytochrome b5 heme-binding domain-containing protein. (541 aa)
	PV08_01690	Pex2_Pex12 domain-containing protein. (465 aa)
	PV08_01976	Acetoacetate-CoA ligase. (694 aa)
	PV08_11626	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (631 aa)
	PV08_11646	Uncharacterized protein. (306 aa)
	PV08_10858	Uncharacterized protein. (318 aa)
	PV08_09809	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (436 aa)
	PV08_07928	Uncharacterized protein. (313 aa)
	PV08_08334	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (699 aa)
	PV08_06607	Zn(2)-C6 fungal-type domain-containing protein. (764 aa)
	PV08_07547	APH domain-containing protein. (371 aa)
	PV08_07864	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (530 aa)
	PV08_05302	Uncharacterized protein. (471 aa)
	PV08_05498	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
	PV08_05817	AMP-binding domain-containing protein. (552 aa)
	PV08_06328	Uncharacterized protein. (540 aa)
	PV08_06358	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (246 aa)
	PV08_03795	RING-type domain-containing protein. (389 aa)
	PV08_04168	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (709 aa)
	PV08_04802	CitMHS domain-containing protein. (569 aa)
	PV08_01007	Uncharacterized protein. (425 aa)
	PV08_11784	ETF domain-containing protein. (349 aa)
	PV08_11305	Uncharacterized protein. (845 aa)
	PV08_11517	Uncharacterized protein. (441 aa)
	PV08_10247	Uncharacterized protein. (426 aa)
	PV08_10884	Uncharacterized protein. (392 aa)
	PV08_09299	AMP-binding domain-containing protein. (549 aa)
	PV08_09835	WD_REPEATS_REGION domain-containing protein. (339 aa)
	PV08_09871	Uncharacterized protein. (316 aa)
	PV08_08370	Uncharacterized protein. (443 aa)
	PV08_08192	Uncharacterized protein. (755 aa)
	PV08_08277	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (576 aa)
	PV08_08661	Zn(2)-C6 fungal-type domain-containing protein. (649 aa)
	PV08_08951	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
	PV08_07237	Uncharacterized protein. (286 aa)
	PV08_07543	Uncharacterized protein. (456 aa)
	PV08_07279	Uncharacterized protein. (287 aa)
	PV08_07479	Uncharacterized protein. (167 aa)
	PV08_07905	Uncharacterized protein. (613 aa)
	PV08_07717	Uncharacterized protein. (445 aa)
	PV08_05676	Uncharacterized protein. (295 aa)
	PV08_05943	Uncharacterized protein. (424 aa)
	PV08_06326	Pyruvate carboxyltransferase domain-containing protein. (650 aa)
	PV08_06331	Uncharacterized protein. (794 aa)
	PV08_04159	Uncharacterized protein. (422 aa)
	PV08_03863	Uncharacterized protein. (291 aa)
	PV08_04000	PKS_ER domain-containing protein. (411 aa)
	PV08_04045	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (518 aa)
	PV08_04166	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (416 aa)
	PV08_11955	Uncharacterized protein. (596 aa)
	PV08_11306	Uncharacterized protein. (573 aa)
	PV08_10183	Uncharacterized protein. (286 aa)
	PV08_02738	Pex14_N domain-containing protein. (394 aa)
	PV08_02934	Uncharacterized protein. (324 aa)
	PV08_03713	Zn(2)-C6 fungal-type domain-containing protein. (733 aa)
	PV08_03377	Uncharacterized protein. (636 aa)
	PV08_00037	Uncharacterized protein. (400 aa)
	PV08_01035	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
	PV08_01853	SH3 domain-containing protein. (475 aa)
	PV08_08702	Uncharacterized protein. (454 aa)
	PV08_01800	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (297 aa)
	PV08_06085	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
	PV08_03767	Uncharacterized protein. (566 aa)
	PV08_02366	Uncharacterized protein. (313 aa)
	PV08_02662	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (459 aa)
	PV08_01322	ANK_REP_REGION domain-containing protein. (159 aa)
	PV08_01719	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (282 aa)
	PV08_01959	Uncharacterized protein. (433 aa)
	PV08_02089	Uncharacterized protein. (269 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00037	PV08_00053	A0A0D2BLM7	A0A0D1YW46	Uncharacterized protein.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.479
PV08_00037	PV08_00676	A0A0D2BLM7	A0A0D1YXV2	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.599
PV08_00037	PV08_01007	A0A0D2BLM7	A0A0D2A6P2	Uncharacterized protein.	Uncharacterized protein.	0.762
PV08_00037	PV08_01035	A0A0D2BLM7	A0A0D2BPK6	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.841
PV08_00037	PV08_01041	A0A0D2BLM7	A0A0D1YYW3	Uncharacterized protein.	ETF domain-containing protein.	0.833
PV08_00037	PV08_01273	A0A0D2BLM7	A0A0D1YZF7	Uncharacterized protein.	Uncharacterized protein.	0.689
PV08_00037	PV08_01322	A0A0D2BLM7	A0A0D2CAZ2	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.559
PV08_00037	PV08_01690	A0A0D2BLM7	A0A0D1Z0I3	Uncharacterized protein.	Pex2_Pex12 domain-containing protein.	0.460
PV08_00037	PV08_01719	A0A0D2BLM7	A0A0D2CCC2	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.621
PV08_00037	PV08_01800	A0A0D2BLM7	A0A0D2BS16	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.826
PV08_00037	PV08_01853	A0A0D2BLM7	A0A0D2BQK7	Uncharacterized protein.	SH3 domain-containing protein.	0.444
PV08_00037	PV08_01976	A0A0D2BLM7	A0A0D1Z160	Uncharacterized protein.	Acetoacetate-CoA ligase.	0.439
PV08_00037	PV08_02089	A0A0D2BLM7	A0A0D2CDD2	Uncharacterized protein.	Uncharacterized protein.	0.613
PV08_00037	PV08_02366	A0A0D2BLM7	A0A0D2C3A3	Uncharacterized protein.	Uncharacterized protein.	0.522
PV08_00037	PV08_02662	A0A0D2BLM7	A0A0D2C419	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.834
PV08_00037	PV08_02738	A0A0D2BLM7	A0A0D2BIQ2	Uncharacterized protein.	Pex14_N domain-containing protein.	0.471
PV08_00037	PV08_02934	A0A0D2BLM7	A0A0D2BJ85	Uncharacterized protein.	Uncharacterized protein.	0.645
PV08_00037	PV08_03377	A0A0D2BLM7	A0A0D2BKJ4	Uncharacterized protein.	Uncharacterized protein.	0.634
PV08_00037	PV08_03418	A0A0D2BLM7	A0A0D1YV20	Uncharacterized protein.	Uncharacterized protein.	0.883
PV08_00037	PV08_03423	A0A0D2BLM7	A0A0D1YV24	Uncharacterized protein.	SCP2 domain-containing protein.	0.718