(16 nodes) Valine catabolic process, and acetate-CoA ligase activity network (Exophiala spinifera)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PV08_05871	Methylmalonate-semialdehyde dehydrogenase (Acylating). (593 aa)
	PV08_05992	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family. (490 aa)
	PV08_05157	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	PV08_01616	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (480 aa)
	PV08_11232	Uncharacterized protein. (697 aa)
	PV08_09093	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	PV08_09705	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	PV08_08836	Uncharacterized protein. (325 aa)
	PV08_05300	Methylmalonate-semialdehyde dehydrogenase (Acylating). (536 aa)
	PV08_06356	Uncharacterized protein. (617 aa)
	PV08_11251	Uncharacterized protein. (335 aa)
	PV08_04749	Uncharacterized protein. (329 aa)
	PV08_00052	Uncharacterized protein. (353 aa)
	PV08_00590	Acetyl-CoA hydrolase. (525 aa)
	PV08_08026	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
	PV08_05769	Acetyl-coenzyme A synthetase. (670 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00052	PV08_01616	A0A0D2BLP4	A0A0D2A8F1	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.876
PV08_00052	PV08_05300	A0A0D2BLP4	A0A0D2B9B9	Uncharacterized protein.	Methylmalonate-semialdehyde dehydrogenase (Acylating).	0.852
PV08_00052	PV08_05871	A0A0D2BLP4	A0A0D1YLA3	Uncharacterized protein.	Methylmalonate-semialdehyde dehydrogenase (Acylating).	0.743
PV08_00052	PV08_05992	A0A0D2BLP4	A0A0D1ZT25	Uncharacterized protein.	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	0.631
PV08_00052	PV08_08026	A0A0D2BLP4	A0A0D2BNZ8	Uncharacterized protein.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.594
PV08_00052	PV08_08836	A0A0D2BLP4	A0A0D2B4M4	Uncharacterized protein.	Uncharacterized protein.	0.600
PV08_00052	PV08_09093	A0A0D2BLP4	A0A0D2AZC7	Uncharacterized protein.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.710
PV08_00052	PV08_09705	A0A0D2BLP4	A0A0D2B0F3	Uncharacterized protein.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.631
PV08_00590	PV08_01616	A0A0D2BNC0	A0A0D2A8F1	Acetyl-CoA hydrolase.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.512
PV08_00590	PV08_05157	A0A0D2BNC0	A0A0D1ZZ78	Acetyl-CoA hydrolase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.514
PV08_00590	PV08_05300	A0A0D2BNC0	A0A0D2B9B9	Acetyl-CoA hydrolase.	Methylmalonate-semialdehyde dehydrogenase (Acylating).	0.743
PV08_00590	PV08_05769	A0A0D2BNC0	A0A0D2BWQ0	Acetyl-CoA hydrolase.	Acetyl-coenzyme A synthetase.	0.848
PV08_00590	PV08_05871	A0A0D2BNC0	A0A0D1YLA3	Acetyl-CoA hydrolase.	Methylmalonate-semialdehyde dehydrogenase (Acylating).	0.685
PV08_00590	PV08_05992	A0A0D2BNC0	A0A0D1ZT25	Acetyl-CoA hydrolase.	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	0.688
PV08_00590	PV08_09093	A0A0D2BNC0	A0A0D2AZC7	Acetyl-CoA hydrolase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.745
PV08_00590	PV08_09705	A0A0D2BNC0	A0A0D2B0F3	Acetyl-CoA hydrolase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.688
PV08_00590	PV08_11232	A0A0D2BNC0	A0A0D2AUT1	Acetyl-CoA hydrolase.	Uncharacterized protein.	0.814
PV08_01616	PV08_00052	A0A0D2A8F1	A0A0D2BLP4	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.876
PV08_01616	PV08_00590	A0A0D2A8F1	A0A0D2BNC0	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Acetyl-CoA hydrolase.	0.512
PV08_01616	PV08_04749	A0A0D2A8F1	A0A0D2BG37	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.851