32 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_11782	Uncharacterized protein. (381 aa)
	PV08_09537	Uncharacterized protein. (355 aa)
	PV08_07425	Ribosome biogenesis protein nsa2. (261 aa)
	PV08_04467	Protein MAK16; Belongs to the MAK16 family. (327 aa)
	PV08_04926	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (221 aa)
	PV08_02368	Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (702 aa)
	PV08_10838	C2H2-type domain-containing protein. (113 aa)
	PV08_08244	TRASH domain-containing protein. (213 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (681 aa)
	PV08_02795	Uncharacterized protein; Belongs to the DEAD box helicase family. (612 aa)
	PV08_00787	Brix domain-containing protein. (457 aa)
	PV08_00857	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (659 aa)
	PV08_11366	RRM domain-containing protein. (660 aa)
	PV08_09342	Brix domain-containing protein. (343 aa)
	PV08_09264	Uncharacterized protein. (382 aa)
	PV08_08317	Uncharacterized protein. (262 aa)
	PV08_07785	CP-type G domain-containing protein. (549 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (781 aa)
	PV08_05658	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (188 aa)
	PV08_06256	Uncharacterized protein. (231 aa)
	PV08_10734	RNA helicase. (627 aa)
	PV08_03084	Uncharacterized protein. (710 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (248 aa)
	PV08_01652	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (428 aa)
	PV08_02135	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (250 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (830 aa)
	PV08_05657	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (685 aa)
	PV08_04094	AB hydrolase-1 domain-containing protein. (380 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (459 aa)
	PV08_05034	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (583 aa)
	PV08_00719	Brix domain-containing protein. (382 aa)
	PV08_00754	rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (127 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERB1	NOP7	A0A0D2B947	A0A0D1ZYX1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
ERB1	PV08_00719	A0A0D2B947	A0A0D2C992	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.987
ERB1	PV08_00787	A0A0D2B947	A0A0D2A600	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Brix domain-containing protein.	0.976
ERB1	PV08_00857	A0A0D2B947	A0A0D2A660	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.996
ERB1	PV08_01652	A0A0D2B947	A0A0D2BQ61	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.748
ERB1	PV08_02135	A0A0D2B947	A0A0D2BT28	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.996
ERB1	PV08_02368	A0A0D2B947	A0A0D1YS75	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosomal RNA small subunit methyltransferase B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.996
ERB1	PV08_02795	A0A0D2B947	A0A0D2A0P0	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.983
ERB1	PV08_03084	A0A0D2B947	A0A0D2BJL7	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.995
ERB1	PV08_04094	A0A0D2B947	A0A0D2BZX6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	AB hydrolase-1 domain-containing protein.	0.961
ERB1	PV08_04467	A0A0D2B947	A0A0D1YPW9	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Protein MAK16; Belongs to the MAK16 family.	0.966
ERB1	PV08_04926	A0A0D2B947	A0A0D1YR45	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.827
ERB1	PV08_05034	A0A0D2B947	A0A0D2C2H3	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.991
ERB1	PV08_05657	A0A0D2B947	A0A0D2BWG8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.992
ERB1	PV08_05658	A0A0D2B947	A0A0D2BAK6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.988
ERB1	PV08_06256	A0A0D2B947	A0A0D2BC53	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.979
ERB1	PV08_07425	A0A0D2B947	A0A0D1YI76	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Ribosome biogenesis protein nsa2.	0.990
ERB1	PV08_07785	A0A0D2B947	A0A0D2B819	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	CP-type G domain-containing protein.	0.998
ERB1	PV08_08244	A0A0D2B947	A0A0D1ZJS8	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	TRASH domain-containing protein.	0.991
ERB1	PV08_08317	A0A0D2B947	A0A0D2B3C6	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Uncharacterized protein.	0.992