85 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_01328	Uncharacterized protein. (422 aa)
	PV08_01748	Uncharacterized protein. (481 aa)
	PV08_01552	Uncharacterized protein. (205 aa)
	PV08_00993	Uncharacterized protein. (724 aa)
	PV08_09841	RNase III domain-containing protein. (313 aa)
	PV08_00823	ATP-dependent RNA helicase dbp2; Belongs to the DEAD box helicase family. (528 aa)
	PV08_00518	RPOL4c domain-containing protein. (152 aa)
	PAN3	PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...] (642 aa)
	PV08_10714	Uncharacterized protein. (629 aa)
	PV08_03127	Uncharacterized protein. (529 aa)
	PV08_02678	KH_dom_type_1 domain-containing protein. (246 aa)
	PV08_10343	Uncharacterized protein. (448 aa)
	PV08_02811	NTP_transf_9 domain-containing protein. (163 aa)
	PV08_02586	PUM-HD domain-containing protein. (741 aa)
	PV08_05083	Uncharacterized protein; Belongs to the RNR ribonuclease family. (1005 aa)
	PV08_05008	Uncharacterized protein. (650 aa)
	PV08_04113	RRM domain-containing protein. (710 aa)
	PV08_06289	Uncharacterized protein. (279 aa)
	PAN2	PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1201 aa)
	PV08_07427	Uncharacterized protein. (1268 aa)
	PV08_07117	Uncharacterized protein. (268 aa)
	LSM1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation. (175 aa)
	PV08_06654	Protein vts1. (611 aa)
	PV08_08934	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1398 aa)
	PV08_08618	Helicase ATP-binding domain-containing protein. (1072 aa)
	PV08_08142	Uncharacterized protein. (303 aa)
	PV08_09549	Uncharacterized protein. (1686 aa)
	PV08_09372	Histone H2A; Belongs to the histone H2A family. (138 aa)
	PV08_10992	Sm domain-containing protein. (134 aa)
	PV08_10720	NTP_transf_9 domain-containing protein. (266 aa)
	PV08_10608	S1 motif domain-containing protein. (350 aa)
	PV08_10418	HRDC domain-containing protein. (822 aa)
	PV08_10367	Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (413 aa)
	PV08_11437	Uncharacterized protein. (2310 aa)
	PV08_11207	Uncharacterized protein. (842 aa)
	PV08_11781	Uncharacterized protein. (1191 aa)
	PV08_11926	Ribosomal protein L32. (417 aa)
	PV08_12090	EST1_DNA_bind domain-containing protein. (741 aa)
	PV08_12097	Uncharacterized protein. (661 aa)
	PV08_00962	Uncharacterized protein. (330 aa)
	PV08_00612	S1 domain-containing protein. (167 aa)
	PV08_03697	Uncharacterized protein. (610 aa)
	PV08_03982	Endo/exonuclease/phosphatase domain-containing protein. (687 aa)
	PV08_06516	Uncharacterized protein. (245 aa)
	PV08_07839	Uncharacterized protein. (1402 aa)
	PV08_07627	Nuclear cap-binding protein subunit 2. (180 aa)
	PV08_07552	Uncharacterized protein. (292 aa)
	PV08_07241	PAP-associated domain-containing protein. (1360 aa)
	PV08_07215	Translation elongation factor Tu. (466 aa)
	PV08_07214	HBS1_N domain-containing protein. (367 aa)
	PV08_06847	RNase_PH domain-containing protein. (369 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (128 aa)
	PV08_09240	Nudix hydrolase domain-containing protein. (897 aa)
	PV08_11385	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (1038 aa)
	PV08_11147	Uncharacterized protein. (504 aa)
	PV08_01793	Sec2p domain-containing protein. (274 aa)
	PV08_07230	Mago-bind domain-containing protein. (205 aa)
	PV08_06728	RNase_PH domain-containing protein. (267 aa)
	PV08_08029	RRM domain-containing protein. (687 aa)
	PV08_09371	Uncharacterized protein. (606 aa)
	PV08_10101	Uncharacterized protein. (291 aa)
	PV08_11199	DUF2439 domain-containing protein. (664 aa)
	PV08_02116	PAT1 domain-containing protein. (799 aa)
	PV08_01851	RRM domain-containing protein. (447 aa)
	PV08_01826	Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (207 aa)
	PV08_01625	CULLIN_2 domain-containing protein; Belongs to the cullin family. (896 aa)
	PV08_01156	RAI1 domain-containing protein. (394 aa)
	PV08_01126	Uncharacterized protein. (1089 aa)
	PV08_01116	EST1_DNA_bind domain-containing protein. (787 aa)
	PV08_04121	Uncharacterized protein. (459 aa)
	PV08_06504	Uncharacterized protein. (524 aa)
	PV08_05236	Uncharacterized protein. (1136 aa)
	PV08_02059	Fungal_trans domain-containing protein. (684 aa)
	PV08_01688	Uncharacterized protein. (360 aa)
	PV08_01478	zf-GRF domain-containing protein. (337 aa)
	PV08_01205	RNase_PH domain-containing protein. (363 aa)
	PV08_03406	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (611 aa)
	PV08_03344	RNase_PH domain-containing protein. (258 aa)
	PV08_04979	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (226 aa)
	PV08_04531	PUM-HD domain-containing protein. (890 aa)
	PV08_04255	zf-C3H1 domain-containing protein. (1292 aa)
	PV08_03893	Uncharacterized protein. (397 aa)
	PV08_05804	Tr-type G domain-containing protein. (702 aa)
	PV08_07763	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family. (512 aa)
	PV08_07485	Uncharacterized protein. (1689 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM1	LSM4	A0A0D2B6L3	A0A0D1YFQ5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.973
LSM1	PV08_00823	A0A0D2B6L3	A0A0D2BMS5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	ATP-dependent RNA helicase dbp2; Belongs to the DEAD box helicase family.	0.561
LSM1	PV08_00962	A0A0D2B6L3	A0A0D2A6I5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.817
LSM1	PV08_02116	A0A0D2B6L3	A0A0D1Z1M6	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	PAT1 domain-containing protein.	0.966
LSM1	PV08_02811	A0A0D2B6L3	A0A0D2BHY1	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.809
LSM1	PV08_03982	A0A0D2B6L3	A0A0D1ZVP7	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Endo/exonuclease/phosphatase domain-containing protein.	0.427
LSM1	PV08_04979	A0A0D2B6L3	A0A0D2C2A3	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.	0.534
LSM1	PV08_07427	A0A0D2B6L3	A0A0D2B6V7	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.549
LSM1	PV08_07552	A0A0D2B6L3	A0A0D1ZPL9	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.850
LSM1	PV08_07763	A0A0D2B6L3	A0A0D1YJ66	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	ATP-dependent RNA helicase DHH1; Belongs to the DEAD box helicase family.	0.968
LSM1	PV08_07839	A0A0D2B6L3	A0A0D1ZQK5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Uncharacterized protein.	0.411
LSM1	PV08_08618	A0A0D2B6L3	A0A0D2B420	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Helicase ATP-binding domain-containing protein.	0.550
LSM1	PV08_08934	A0A0D2B6L3	A0A0D2B456	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.919
LSM1	PV08_09240	A0A0D2B6L3	A0A0D1YAL5	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Nudix hydrolase domain-containing protein.	0.850
LSM1	PV08_10720	A0A0D2B6L3	A0A0D2AYE8	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	NTP_transf_9 domain-containing protein.	0.809
LSM1	PV08_10992	A0A0D2B6L3	A0A0D2AZ00	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	Sm domain-containing protein.	0.970
LSM4	LSM1	A0A0D1YFQ5	A0A0D2B6L3	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.	0.973
LSM4	PV08_00823	A0A0D1YFQ5	A0A0D2BMS5	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	ATP-dependent RNA helicase dbp2; Belongs to the DEAD box helicase family.	0.629
LSM4	PV08_00962	A0A0D1YFQ5	A0A0D2A6I5	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.903
LSM4	PV08_01748	A0A0D1YFQ5	A0A0D2BQD3	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.442