31 items (Exophiala spinifera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_10225	Protein kinase domain-containing protein. (574 aa)
	PV08_07845	DUF1767 domain-containing protein. (291 aa)
	PV08_06094	Uncharacterized protein. (417 aa)
	PV08_03791	Uncharacterized protein. (213 aa)
	PV08_04747	Uncharacterized protein. (206 aa)
	PV08_04905	DNA_MISMATCH_REPAIR_2 domain-containing protein. (990 aa)
	PV08_11418	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1668 aa)
	PV08_11523	ERCC4 domain-containing protein. (615 aa)
	PV08_10840	Uncharacterized protein. (810 aa)
	PV08_09505	ERCC4 domain-containing protein. (659 aa)
	PV08_11283	ERCC4 domain-containing protein. (944 aa)
	PV08_07826	Uncharacterized protein. (362 aa)
	PV08_00258	Protein kinase domain-containing protein. (1057 aa)
	PV08_02184	Uncharacterized protein. (418 aa)
	PV08_07825	Uncharacterized protein. (77 aa)
	PV08_09496	Uncharacterized protein. (110 aa)
	PV08_09171	DNA_mis_repair domain-containing protein. (764 aa)
	PV08_11926	Ribosomal protein L32. (417 aa)
	PV08_04892	FHA domain-containing protein. (854 aa)
	PV08_06258	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (617 aa)
	PV08_06173	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	PV08_11024	Uncharacterized protein. (939 aa)
	PV08_11329	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (349 aa)
	PV08_02328	TP6A_N domain-containing protein. (391 aa)
	PV08_04292	Uncharacterized protein. (179 aa)
	PV08_03991	RECA_2 domain-containing protein. (483 aa)
	PV08_07566	Uncharacterized protein. (1835 aa)
	PV08_08323	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (625 aa)
	PV08_09929	DNA_MISMATCH_REPAIR_2 domain-containing protein. (894 aa)
	PV08_09598	Uncharacterized protein. (531 aa)
	PV08_10963	Uncharacterized protein. (245 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV08_00258	PV08_02328	A0A0D2C7X5	A0A0D1YS49	Protein kinase domain-containing protein.	TP6A_N domain-containing protein.	0.422
PV08_00258	PV08_03991	A0A0D2C7X5	A0A0D1YNU8	Protein kinase domain-containing protein.	RECA_2 domain-containing protein.	0.499
PV08_00258	PV08_04292	A0A0D2C7X5	A0A0D1YPI7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.406
PV08_00258	PV08_08323	A0A0D2C7X5	A0A0D1YDN6	Protein kinase domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.509
PV08_00258	PV08_09496	A0A0D2C7X5	A0A0D2B0H5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.428
PV08_00258	PV08_09505	A0A0D2C7X5	A0A0D2BM12	Protein kinase domain-containing protein.	ERCC4 domain-containing protein.	0.715
PV08_00258	PV08_10225	A0A0D2C7X5	A0A0D1Y7N2	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.682
PV08_00258	PV08_10840	A0A0D2C7X5	A0A0D2BJU5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.635
PV08_00258	PV08_11024	A0A0D2C7X5	A0A0D1ZFD4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.635
PV08_00258	PV08_11283	A0A0D2C7X5	A0A0D1Y5Y9	Protein kinase domain-containing protein.	ERCC4 domain-containing protein.	0.661
PV08_00258	PV08_11329	A0A0D2C7X5	A0A0D1ZBF2	Protein kinase domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.606
PV08_00258	PV08_11418	A0A0D2C7X5	A0A0D2BGK0	Protein kinase domain-containing protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.653
PV08_00258	PV08_11523	A0A0D2C7X5	A0A0D2BGV8	Protein kinase domain-containing protein.	ERCC4 domain-containing protein.	0.708
PV08_02184	PV08_09171	A0A0D2CDJ4	A0A0D2AYW2	Uncharacterized protein.	DNA_mis_repair domain-containing protein.	0.495
PV08_02328	PV08_00258	A0A0D1YS49	A0A0D2C7X5	TP6A_N domain-containing protein.	Protein kinase domain-containing protein.	0.422
PV08_02328	PV08_03791	A0A0D1YS49	A0A0D2BCA8	TP6A_N domain-containing protein.	Uncharacterized protein.	0.539
PV08_02328	PV08_03991	A0A0D1YS49	A0A0D1YNU8	TP6A_N domain-containing protein.	RECA_2 domain-containing protein.	0.762
PV08_02328	PV08_04292	A0A0D1YS49	A0A0D1YPI7	TP6A_N domain-containing protein.	Uncharacterized protein.	0.578
PV08_02328	PV08_04747	A0A0D1YS49	A0A0D2BF19	TP6A_N domain-containing protein.	Uncharacterized protein.	0.624
PV08_02328	PV08_04892	A0A0D1YS49	A0A0D1ZYG5	TP6A_N domain-containing protein.	FHA domain-containing protein.	0.432