85 items (Exophiala spinifera) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV08_04922	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1093 aa)
	PV08_02184	Uncharacterized protein. (418 aa)
	PV08_01994	Uncharacterized protein. (1159 aa)
	PV08_01079	Uncharacterized protein. (1666 aa)
	PV08_04035	DNA_MISMATCH_REPAIR_2 domain-containing protein. (1006 aa)
	PV08_04266	Uncharacterized protein. (1424 aa)
	PV08_04905	DNA_MISMATCH_REPAIR_2 domain-containing protein. (990 aa)
	PV08_04920	Uncharacterized protein. (943 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (815 aa)
	PV08_11418	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1668 aa)
	PV08_11513	Uncharacterized protein. (144 aa)
	PV08_02372	Uncharacterized protein. (843 aa)
	PV08_03252	Uncharacterized protein. (1137 aa)
	PV08_10840	Uncharacterized protein. (810 aa)
	PV08_03345	Uncharacterized protein. (1110 aa)
	PV08_00060	DNA repair helicase rad15. (816 aa)
	PV08_03499	Uncharacterized protein. (1306 aa)
	PV08_01436	Uncharacterized protein. (384 aa)
	PV08_01105	SAP domain-containing protein. (678 aa)
	PV08_08356	Uncharacterized protein. (1052 aa)
	PV08_06790	Replication factor C subunit 1. (1080 aa)
	PV08_05475	Uncharacterized protein. (1626 aa)
	PV08_05713	Uncharacterized protein. (912 aa)
	PV08_05144	Uncharacterized protein. (661 aa)
	PV08_02462	Uncharacterized protein. (1073 aa)
	PV08_00298	Uncharacterized protein. (1197 aa)
	PV08_00964	Uncharacterized protein. (1879 aa)
	PV08_11137	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (505 aa)
	PV08_10025	Uncharacterized protein. (186 aa)
	PV08_10406	Uncharacterized protein. (1122 aa)
	PV08_10933	Uncharacterized protein. (469 aa)
	PV08_09558	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (473 aa)
	PV08_09929	DNA_MISMATCH_REPAIR_2 domain-containing protein. (894 aa)
	PV08_08463	Uncharacterized protein. (579 aa)
	PV08_07315	HD domain-containing protein. (241 aa)
	PV08_07566	Uncharacterized protein. (1835 aa)
	PV08_03724	Uncharacterized protein. (871 aa)
	PV08_03991	RECA_2 domain-containing protein. (483 aa)
	PV08_04921	Uncharacterized protein. (621 aa)
	PV08_05176	Uncharacterized protein. (308 aa)
	PV08_02328	TP6A_N domain-containing protein. (391 aa)
	PV08_00250	DNA_mis_repair domain-containing protein. (940 aa)
	PV08_01364	Uncharacterized protein. (484 aa)
	PV08_11329	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (349 aa)
	PV08_10647	DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR). (926 aa)
	PV08_11024	Uncharacterized protein. (939 aa)
	PV08_09190	Uncharacterized protein. (381 aa)
	PV08_09574	RING-type domain-containing protein. (1422 aa)
	PV08_10010	Uncharacterized protein. (1018 aa)
	PV08_07979	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (699 aa)
	PV08_08818	RECA_2 domain-containing protein. (447 aa)
	PV08_06693	Helicase ATP-binding domain-containing protein. (711 aa)
	PV08_07749	Uncharacterized protein. (326 aa)
	PV08_07764	SMC_N domain-containing protein. (1128 aa)
	PV08_05327	Uncharacterized protein. (1032 aa)
	PV08_06027	Uncharacterized protein. (878 aa)
	PV08_06278	Uncharacterized protein. (1052 aa)
	PV08_04691	Uncharacterized protein. (1013 aa)
	PV08_05027	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1247 aa)
	PV08_05092	MutL_C domain-containing protein. (897 aa)
	PV08_02840	Uncharacterized protein. (1545 aa)
	PV08_00832	Uncharacterized protein. (1194 aa)
	PV08_02267	Helicase ATP-binding domain-containing protein. (1253 aa)
	PV08_10209	Helicase ATP-binding domain-containing protein. (831 aa)
	PV08_10289	Rad51 domain-containing protein. (519 aa)
	PV08_10773	Uncharacterized protein. (1582 aa)
	PV08_09171	DNA_mis_repair domain-containing protein. (764 aa)
	PV08_08117	Uncharacterized protein. (1653 aa)
	PV08_08618	Helicase ATP-binding domain-containing protein. (1072 aa)
	PV08_08889	Uncharacterized protein. (1156 aa)
	PV08_07317	Uncharacterized protein. (628 aa)
	PV08_07322	Uncharacterized protein. (1513 aa)
	PV08_07187	Helicase C-terminal domain-containing protein. (764 aa)
	PV08_07653	DNA helicase; Belongs to the MCM family. (1005 aa)
	PV08_07658	Structural maintenance of chromosomes protein. (1206 aa)
	PV08_07439	Helicase C-terminal domain-containing protein. (182 aa)
	PV08_05391	Uncharacterized protein. (1900 aa)
	PV08_05758	Uncharacterized protein. (641 aa)
	PV08_05793	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (456 aa)
	PV08_05808	Helicase ATP-binding domain-containing protein. (2106 aa)
	PV08_05898	Uncharacterized protein. (723 aa)
	PV08_06094	Uncharacterized protein. (417 aa)
	PV08_06394	Uncharacterized protein. (1027 aa)
	PV08_06206	Uncharacterized protein. (385 aa)
	PV08_04254	DNA helicase; Belongs to the MCM family. (947 aa)

Your Current Organism:

Exophiala spinifera

NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MCM7	PV08_01436	A0A0D2BGG8	A0A0D2BPI9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.508
MCM7	PV08_02267	A0A0D2BGG8	A0A0D2AA93	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Helicase ATP-binding domain-containing protein.	0.402
MCM7	PV08_02840	A0A0D2BGG8	A0A0D2A0R9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.544
MCM7	PV08_03724	A0A0D2BGG8	A0A0D1YNA6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.402
MCM7	PV08_03991	A0A0D2BGG8	A0A0D1YNU8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	RECA_2 domain-containing protein.	0.405
MCM7	PV08_04035	A0A0D2BGG8	A0A0D2BE23	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.536
MCM7	PV08_04254	A0A0D2BGG8	A0A0D2BDP8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV08_04905	A0A0D2BGG8	A0A0D2BGE0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.463
MCM7	PV08_05027	A0A0D2BGG8	A0A0D1ZYT8	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.458
MCM7	PV08_05144	A0A0D2BGG8	A0A0D2C2W4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.454
MCM7	PV08_05176	A0A0D2BGG8	A0A0D1YRX9	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.402
MCM7	PV08_05713	A0A0D2BGG8	A0A0D2BWK4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.606
MCM7	PV08_06027	A0A0D2BGG8	A0A0D1ZT81	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.493
MCM7	PV08_06790	A0A0D2BGG8	A0A0D2BS37	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Replication factor C subunit 1.	0.505
MCM7	PV08_07322	A0A0D2BGG8	A0A0D2B6P6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.402
MCM7	PV08_07653	A0A0D2BGG8	A0A0D2B7H0	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	PV08_07658	A0A0D2BGG8	A0A0D2B7H6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Structural maintenance of chromosomes protein.	0.493
MCM7	PV08_07764	A0A0D2BGG8	A0A0D1ZQD2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	SMC_N domain-containing protein.	0.439
MCM7	PV08_09171	A0A0D2BGG8	A0A0D2AYW2	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA_mis_repair domain-containing protein.	0.464
MCM7	PV08_10010	A0A0D2BGG8	A0A0D1ZIQ1	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Uncharacterized protein.	0.402