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PV08_04500 PV08_04500 PV08_08923 PV08_08923 PV08_09199 PV08_09199 PV08_07646 PV08_07646 ADK2 ADK2 PV08_01207 PV08_01207 PV08_10697 PV08_10697 PV08_01069 PV08_01069 PV08_03633 PV08_03633 AAH1-2 AAH1-2 ADK1 ADK1 PV08_00888 PV08_00888 PV08_04724 PV08_04724 PV08_03927 PV08_03927 PV08_05489 PV08_05489 PV08_08891 PV08_08891 PV08_08462 PV08_08462 PV08_09615 PV08_09615 PV08_00792 PV08_00792 PV08_02996 PV08_02996 PV08_02951 PV08_02951 PV08_06308 PV08_06308 PV08_06928 PV08_06928 PV08_06617 PV08_06617
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV08_04500Phosphoribosylamine-glycine ligase. (794 aa)
PV08_08923Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
PV08_09199Uncharacterized protein. (205 aa)
PV08_07646Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (607 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (259 aa)
PV08_01207Amidophosphoribosyltransferase. (597 aa)
PV08_106973-carboxy-cis,cis-muconate cycloisomerase. (450 aa)
PV08_01069Uncharacterized protein; Belongs to the 5'-nucleotidase family. (638 aa)
PV08_03633Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (350 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (279 aa)
PV08_008883-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
PV08_04724Phosphoribosylglycinamide formyltransferase. (246 aa)
PV08_03927PfkB domain-containing protein. (338 aa)
PV08_05489Adenine phosphoribosyltransferase. (214 aa)
PV08_08891Uncharacterized protein. (275 aa)
PV08_08462Guanylate kinase. (207 aa)
PV08_09615Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (618 aa)
PV08_00792AMP deaminase. (1045 aa)
PV08_02996Phosphoribosylformylglycinamidine synthase. (1381 aa)
PV08_02951GMP synthase [glutamine-hydrolyzing]. (545 aa)
PV08_06308Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
PV08_06928Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (305 aa)
PV08_06617Formyltetrahydrofolate deformylase. (281 aa)
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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